RHOBTB3 promotes proteasomal degradation of HIFalpha through facilitating hydroxylation and suppresses the Warburg effect.
Zhang CS, Liu Q, Li M, Lin SY, Peng Y, Wu D, Li TY, Fu Q, Jia W, Wang X, Ma T, Zong Y, Cui J, Pu C, Lian G, Guo H, Ye Z, Lin SC
Cell Res. 2015 Sep;25(9):1025-42. doi: 10.1038/cr.2015.90. Epub 2015 Jul 28.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 246202 | pBOBI N-HA hVHL | Used for transfection of cells for expression N-HA hVHL |
| 246203 | pBOBI N-FLAG hVHL | Used for transfection of cells for expression N-FLAG hVHL |
| 246204 | pcDNA 3.3 N-FLAG VHL | Used for transfection of cells for expression N-FLAG VHL |
| 246205 | pBOBI N-FLAG LIMD1 | Used for transfection of cells for expression N-FLAG LIMD1 |
| 246206 | pBOBI N-HA LIMD1 | Used for transfection of cells for expression N-HA LIMD1 |
| 246207 | pcDNA 3.3 N-HA RhoBTB3 | Used for transfection of cells for expression N-HA RhoBTB3 |
| 246208 | pcDNA 3.3 N-MYC RhoBTB3 | Used for transfection of cells for expression N-MYC RhoBTB3 |
| 246209 | pBOBI N-HA EGLN1 | Used for transfection of cells for expression N-HA EGLN1 |
| 246210 | pBOBI C-FLAG EGLN1 | Used for transfection of cells for expression C-FLAG EGLN1 |
| 246211 | pBOBI N-HA HIF2a | Used for transfection of cells for expression N-HA HIF2a |
| 246212 | pBOBI N-FLAG HIF2a | Used for transfection of cells for expression N-FLAG HIF2a |
| 246213 | pBOBI no tag hHIF1a | Used for transfection of cells for expression hHIF1a |
| 246214 | pcDNA 3.3 N-HA HIF1a | Used for transfection of cells for expression N-HA HIF1a |
| 246216 | CMV5 N-HA hHIF1a P402A | Used for transfection of cells for expression N-HA hHIF1a P402A |
| 246219 | pcDNA 3.3 N-FLAG hARNT | Used for transfection of cells for expression N-FLAG hARNT |