Jesse Engreitz Lab: Rewriting regulatory DNA to dissect and reprogram gene expression.
Martyn GE, Montgomery MT, Jones H, Guo K, Doughty BR, Linder J, Bisht D, Xia F, Cai XS, Chen Z, Cochran K, Lawrence KA, Munson G, Pampari A, Fulco CP, Sahni N, Kelley DR, Lander ES, Kundaje A, Engreitz JM
Cell. 2025 Jun 12;188(12):3349-3366.e23. doi: 10.1016/j.cell.2025.03.034. Epub 2025 Apr 16.
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PubMed
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 255532 | sgOpti-tevoPQ1 | lenti virus vector expressing a prime editing guide RNA under a human U6 promoter. Contains a truncated evoPQ1 sequence at the 3' end of the pegRNA which was shown to improve editing efficiency. |