TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation.
Liu Z, Chen S, Wang W, Zhang F, Wang Q, Walkiewicz G, Hossen F, Zhou J, Wang Y, Sun Y
Cell Stem Cell, 2026
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 250590 | TIGRa | Expresses the TIGRa (dParTasR-VPR) in mammalian cells for transcriptional activation |
| 250591 | TIGRa-Mini | Expresses the TIGRa-Mini (dParTasR-NFZ) in mammalian cells for transcriptional activation |
| 250592 | TIGRa-Pro | Expresses the TIGRa-Pro (dParTasR-NFZP) in mammalian cells for transcriptional activation |
| 250593 | TIGRa-Ultra | Expresses the TIGRa-Ultra (Aho7c-dParTasR-NFZP) in mammalian cells for transcriptional activation |
| 250595 | AAV-TIGRa-Pro-U6-CaMKII | Expresses the AAV-TIGRa-Pro-U6-CaMKII for AAV package |
| 250596 | dTaTasR-VPR | Expresses the dTaTasR-VPR in mammalian cells for transcriptional activation |
| 250597 | U6-tigRNA (empty) | Empty U6-tigRNA expression vector for tigRNA sequence insertion (BbsI restriction site) |
| 250598 | dAsCas12f1-VPR | Expresses the dAsCas12f1-VPR in mammalian cells for transcriptional activation |
| 250599 | denAsCas12f1-VPR (HKRA) | Expresses the denAsCas12f1-VPR (HKRA) in mammalian cells for transcriptional activation |
| 250600 | dAcCas12n-VPR | Expresses the dAcCas12n-VPR in mammalian cells for transcriptional activation |
| 250601 | dIscB-VPR | Expresses the dIscB-VPR in mammalian cells for transcriptional activation |
| 250602 | denIscB-VPR | Expresses the denIscB-VPR in mammalian cells for transcriptional activation |
| 250603 | dIscBQM-VPR | Expresses the dIscBQM-VPR in mammalian cells for transcriptional activation |
| 250604 | dTnpB-VPR | Expresses the dTnpB-VPR in mammalian cells for transcriptional activation |
| 250605 | EBNA-TIGRa-Ultra | Expresses the EBNA-TIGRa-Ultra in mammalian cells for reprogramming |
| 250606 | EBNA-TA-7 targets | Expresses the EBNA-TA-7 targets in mammalian cells for for reprogramming |