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Lior Nissim Lab: Modular Scalable Synthetic Gene Circuits for Complex Functions Within ‎Minimal Computational Layers in Human Cells

Nissim Lab
unpublished

Plasmids from Article

ID Plasmid Purpose
251264pKR3:SSX1p-mK2-Ex1-(5'D)-ID-AFP BD-S(50bp, 30%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251265pKR4:H2A1p-(linker2)-AFP BD-AS(50bp)2mm(18-19)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251266pKR5:H2A1p-(linker2)-AFP BD-AS(1-50bp)2mm(18-19)-(linker3)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251267pKR7:H2A1p-(linker2)-AFP BD-AS(50bp)2mm(18-19)-(linker3)-(Canonical 3'SE V2 mutated PPT)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251268pKR9:H2A1p-(linker2)-BD AFP-AS(21-50bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251269pKR10:SSX1p-mK-Ex1-(5'D)-AFP BD-S (21-50bp)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251270pKR12:H2A1p-(linker2)-AFP BD-AS (1-30bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251271pKR13:SSX1p-mK2-Ex1-(5'D)-ID-AFP BD-S (1-30bp)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251272pKR14:SSX1p-mK2-Ex1-(5'D)-ID-AFP BD-S (50bp)-(linker5[20bp])-AFP BD-S (50bp, 30%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251273pKR15:SSX1p-mK2-Ex1-(5'D)-ID-BD1-S(50bp, 50%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251274pKR16:H2A1p-(linker2)-BD1-AS(50bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251275pKR17:SSX1p-mK2-Ex1-(5'D)-ID-BD2-S(50bp 30%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251276pKR18:H2A1p-(linker2)-BD2-AS (50bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251277pKR19:SSX1p-mK2-Ex1-(5'D)-ID-BD3-S-(30bp 50%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251278pKR20:H2A1p-(linker2)-BD3-AS (30bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251279pKR21:SSX1p-mK2-Ex1-(5'D)-ID-BD4-S-(30bp 30%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251280pKR22:H2A1p-(linker2)-BD4-AS (30bp complement)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251281pKR38:H2A1p-(linker2)-AFP BD-AS(50bp)mm(18,19)-(linker3)-(mutated BP Canonical 3'SE V3)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251282pKR69:H2A1p-(linker2 [10bp])-AFP BD-AS(50bp)2mm(18-19)-(linker3)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251283pKR71:H2A1p-(linker2)-AFP BD-AS(50bp)2mm(18-19)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251284pKR72:H2A1p-AFP BD-AS(50bp)2mm(18-19)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251285pKR73:SSX1p-mK2-Ex1-(5'D)-AFP BD-S(50bp, 30%GC)-(linker1)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251286pKR74:SSX1p-mK2-Ex1-(5'D)-ID-AFP BD-S(50bp, 30%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251287pKR75:SSX1p-mK2-Ex1-(5'D)-AFP BD-S(50bp, 30%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251288pKR78:SSX1p-mK2-Ex1-(5'D)-ID-BD6-S (50bp)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251289pKR80:H2A1p-BD6-AS (50bp)2mm(18-19)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251290pKR81:SSX1p-mK2-Ex1-(5'D)-ID-BD5-S(50bp, 50%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251291pKR83:H2A1p-BD5-AS(50bp, 50%GC)2mm(18-19)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251292pKR84:SSX1p-mK2-Ex1-(5'D)-ID-BD7-S (30bp, 36%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251293pKR85:H2A1p-BD7-AS (30bp)2mm(12-13)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251294pKR86:SSX1p-mK2-Ex1-(5'D)-ID-BD8-S (30bp, 36%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251295pKR87:H2A1p-BD8-AS (30bp)2mm(12-13)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251296pKR88:SSX1p-mK2-Ex1-(5'D)-ID-BD9-S (30bp, 36%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251297pKR89:H2A1p-BD9-AS (30bp)2mm(12-13)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251298pKR90:SSX1p-mK2-Ex1-(5'D)-ID-BD10-S (30bp, 30%GC)-pATrans-splicing expression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251299pKR91:H2A1p-BD10-AS (30bp)2mm(12-13)-(Canonical 3'SE V1)-mK2-Ex2-(linker4)-pATrans-splicing expression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251300pRZ111:G8p-EYFP-pAExpression of EYFP under G8p promoter for use in synthetic gene circuits
251301pRZ134:CMVp-BD9-AS-(3'SE)-GAD-EX2-pAExpression of GAD-Ex2 under CMVp promoter for use in synthetic gene circuits
251302pRZ135:CMVp-GAD-EX1-(5'D)-BD9-S-pAExpression of GAD-Ex1 under CMVp promoter for use in synthetic gene circuits
251303pRZ138:CMVp-GAD-Ex1-(5'D)-BD6-S-pAExpression of GAD-Ex1 under CMVp promoter for use in synthetic gene circuits
251304pRZ139:CMVp-EC-Ex1-(5'D)-BD5-S-pAExpression of ECFP-Ex1 under CMVp promoter for use in synthetic gene circuits
251305pRZ145:CMVp-BD5-AS-(3'SE)-EC-Ex2-pAExpression of ECFP-Ex2 under CMVp promoter for use in synthetic gene circuits
251306pRZ146:CMVp-BD6-AS-(3'SE)-GAD-Ex2-pAExpression of GAD-Ex2 under CMVp promoter for use in synthetic gene circuits
251307pRZ150:CMVp-mK2-Ex1-miRS1-mK2-Ex2-PEST-miRS2-BSs-miRS3-BSs-pAExpression of mKate2 under CMVp promoter for use in synthetic gene circuits
251308pRZ151:CMVp-BD9-AS-(3'SE)-EC-Ex2-pAExpression of ECFP-Ex2 under CMVp promoter for use in synthetic gene circuits
251309pRZ153:CMVp-EC-Ex1-(5'D)-BD9-S-pAExpression of ECFP-Ex1 under CMVp promoter for use in synthetic gene circuits
251310pRZ171:CMVe-G3BSs-TATA-mK2-Ex1-miRS2-mK2-Ex2-miRS1-BSs-miRS3-BSs-pAExpression of mKate2 under CMVe promoter for use in synthetic gene circuits
251311pRZ180:[pA-BD9-S-BD5-S-(5'D)-EC-Ex1]-CMVp-[(G3p)RC-mK2-Ex1-miRS2-mK2-Ex2-miRS1-BSs-miRS3-BSs-pA]Expression of mKate2 Exon 1 and 2 and ECFP-Ex1 for use in synthetic gene circuits
251312pRZ212:CMVp-GAD-pAExpression of GAD under CMVp promoter for use in synthetic gene circuits
251313pRZ230:CMVe-G3BSs-TATA-mKate2-pAExpression of mKate2 under CMVe promoter for use in synthetic gene circuits
251314pRZ231:Inactive Control-G3BSs-TATA-mKate2-pAInactive Control for mKate2 for use in synthetic gene circuits
251315pRZ232:CMVe-Spacer-TATA-mKate2-pAExpression of mKate2 under CMVe promoter for use in synthetic gene circuits
251316pRZ333:CMVp-Sirius-miRS1-BSs-miRS2-BSsExpression of Sirius under CMVp promoter for use in synthetic gene circuits
251317pRZ234:H2A1p-BD6-AS-3'SE-mK-EX2-3*miRS1-BS-pAExpression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251318pRZ235:CMVp-EC-EX1-miRS1-EC-EX2-pAExpression of ECFP under CMVp promoter for use in synthetic gene circuits
251319pRZ241:SSX1p-GAD-EX1-5'D-ID-BD6-S(50bp)Expression of GAD-EX1 under SSX1p promoter for use in synthetic gene circuits
251320pRZ242:H2A1p-BD6-AS(50bp)-Canonical 3'SE V1-GAD-EX2-linker4-pAExpression of GAD-EX2 under H2A1p promoter for use in synthetic gene circuits
251321pRZ274:SSX1p-mK2-Ex1-ID-AFP BD-S-(linker1)-pAExpression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251322pRZ275:H2A1-linker2-AFP BD-AS-linker3-mK2-Ex2-linker4-pAExpression of mK2-Ex2 under H2A1 promoter for use in synthetic gene circuits
251323pRZ314:CMVp-mK2-Ex1-(5'D)-ID-BD6-S(50bp)-pAExpression of mK2-Ex1 under CMVp promoter for use in synthetic gene circuits
251324pRZ315:CMVp-BD6-AS (50bp)2mm(18-19)-(Canonical V13'SE)-mK2-Ex2-(linker4)-pAExpression of mK2-Ex2 under CMVp promoter for use in synthetic gene circuits
251325pRZ330:CMVp-mK-Ex1-miRS3-mK-Ex2-PEST-miRS1-BSs-miRS2-BSs-pAExpression of mKate2 under CMVp promoter for use in synthetic gene circuits
251326pRZ334:CMVp-BD6-AS-(3'SE)-EC-Ex2-miRS2-BSs-pAExpression of ECFP-Ex2 under CMVp promoter for use in synthetic gene circuits
251327pRZ335:CMVp-BD5-AS-(3'SE)-mK2-Ex2-miRS1-BSs-pAExpression of mK2-Ex2 under CMVp promoter for use in synthetic gene circuits
251328pRZ336:CMVp-EC-Ex1-(5'D)-miRS1-(3'SE)-BD6-S-pAExpression of ECFP-Ex1 under CMVp promoter for use in synthetic gene circuits
251329pRZ337:CMVp-mK2-Ex1-(5'D)-miRS2-(3'SE)-BD5-S-pAExpression of mK2-Ex1 under CMVp promoter for use in synthetic gene circuits
251330pRZ365:CMVe-Spacer(80bp)-TATA-mK2-Ex1-miRS2-mK2-Ex2-miRS1-BSs-pAExpression of mKate2 under CMVe promoter for use in synthetic gene circuits
251331pRZ366:CMVp-mK2-Ex1-miRS1-mK2-Ex2-PEST-miRS2-BSs-pAExpression of mKate2 under CMVp promoter for use in synthetic gene circuits
251332pRZ385:CMVp-EC-Ex1-(5'D)-ID-BD6-S(50bp)-pAExpression of ECFP-Ex1 under CMVp promoter for use in synthetic gene circuits
251333pRZ386:CMVp-BD6-AS (50bp)2mm(18-19)-(Canonical 3'SE V1)-EC-Ex2-pAExpression of ECFP-Ex2 under CMVp promoter for use in synthetic gene circuits
251334pRZ427:Inactive Control-mKate2Inactive Control of mKate2 for use in synthetic gene circuits
251335pRZ432:SSX1p-mK2-Ex1-(5'D)-ID-(linker1)-pAExpression of mK2-Ex1 under SSX1p promoter for use in synthetic gene circuits
251336pRZ433:H2A1p-(linker2)-(linker3)-(AFP 3'SE)-mK2-Ex2-(linker4)-pAExpression of mK2-Ex2 under H2A1p promoter for use in synthetic gene circuits
251337pRZ500:G5p-mKate2-pAExpression of mKate2 under G5p promoter for use in synthetic gene circuits
251338pRZ501:G5p-IL15-pAExpression of IL-15 under G5p promoter for use in synthetic gene circuits

Antibodies from Article