Integrating artificial intelligence and optogenetics for Parkinson's disease diagnosis and therapeutics in male mice.

Hyeon B, Shin J, Lee JH, Kim W, Kwon J, Lee H, Kim DG, Kim CY, Choi S, Jeong JW, Kim KS, Lee CJ, Kim D, Heo WD
Nat Commun. 2025 Aug 21;16(1):7797. doi: 10.1038/s41467-025-63025-w. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
253534	AAV-hSyn1-DIO-optoRet(WT)	optogenetic activation of RET downstream signalling
253535	AAV-hSyn-hA53T	overexpression of a human mutated form of aSynuclein (A53T)