D. James Surmeier Lab: State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson's disease.

Zhai S, Cui Q, Wokosin D, Sun L, Tkatch T, Crittenden JR, Graybiel AM, Surmeier DJ
Sci Adv. 2025 Dec 5;11(49):eadv8224. doi: 10.1126/sciadv.adv8224. Epub 2025 Dec 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
245385	pFB-hSyn-SaCas9-mWPRE-hGHpA	CRISPR-SaCas9 is used for in vivo genome-editing tool. Used to locate and cleave specific double-stranded DNA sequences.
248064	pFB-hSyn-DIO-saCAS-minWPRE	CRISPR-SaCas9 for in vivo genome editing. Used to locate and cleave specific double-stranded DNA sequences.