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A compact base editor rescues AATD-associated liver and lung disease in mouse models.

Gao J, Bamidele N, Pires-Ferreira D, Zheng C, Destefano A, Cheng H, Tang Q, Cao Y, Xie J, Gao G, Gruntman A, Sontheimer E, Flotte TR, Xue W
Mol Ther. 2025 Nov 5;33(11):5817-5828. doi: 10.1016/j.ymthe.2025.08.040. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
256758PiZ ABEfor human piz allele editing

Antibodies from Article