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Edward Avezov Lab: Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability.

Davi V, Parutto P, Zhang Y, Konno T, Crapart C, Pereira R, Franklin JP, Awadelkareem MA, Maddison DC, Devine MJ, Gomes ER, Chambers J, Koslover E, Avezov E
Adv Sci (Weinh). 2026 Mar 31:e21101. doi: 10.1002/advs.202521101. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
254290pLV_TRE3G_Halo-Sec61βLentiviral and DOX-inducible expression verctor of human Sec61b, Halo Tag fused to N'
254291pLV_TRE3G_RTN3A-HaloExpresses human Reticulon3A-TEV-HaloTag under DOX-inducible promoter in lentiviral backbone
254292pLV_TRE3G_Halo-NeuroserpinG392EExpresses Neuroserpin G392E-HaloTag under Dox-inducible promoter in lentiviral backbone
254293pLV_TRE3G_ ER-GCaMP3cytosolic GCaMP3 anchored to ER membrane in pLV backbone and DOX-inducible promoter
254294pLV_TRE3G_GCaMP8mGCaMP8m under DOX-inducible promoter in lentiviral backbone
254296pLV_TRE3G_R-CEPIA1erR-CEPIA1er under TRE3G promoter in lentiviral backbone
254297pLV_TRE3G_GFP-MAPPERlentiviral expresion vector of GFP-MAPPER under Dox-inducible promoter
254298pLV_TRE3G_ER-LAR-GECO1ER-LAR-GECO1 under TRE3G promoter in lentiviral backbone
254299pLV_TRE3G_ATL1K80A-Haloexpresses human ATL1 with the K80A mutation under Dox inducible promoter in lentiviral backbone

Antibodies from Article