Force-Induced Ankle Opening Reveals Mechanical Stabilization of the Ankle of Human beta-Cardiac Myosin.
Deopa SPS, Bjorkman KK, Edwards DT, LeBlanc MA, Buvoli M, Oakes SH, Dzuba B, Karabina A, Leinwand LA, Perkins TT
ACS Nano. 2026 Jun 9;20(22):15982-16000. doi: 10.1021/acsnano.5c22720. Epub 2026 May 21.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 257334 | RLC-ELP-ybbR-LA-GB1-GB1-Xmod-DocIII-Ctag | Polyprotein for applying force to the N- and C-termini of the lever arm in the RLC complex of human β-cardiac myosin |
| 257335 | LA-ELP-ybbR-RLC-ddfln4-Xmod-DocIII-Ctag | Polyprotein for applying force to the N- and C-termini of the RLC in the RLC complex of human β-cardiac myosin |
| 257336 | ybbR-ddfln4-RLC-ELP-LA-Xmod-DocIII-Ctag | Polyprotein for applying force to the N-terminus of the RLC and the C-terminus of the lever arm of the RLC complex of human β-cardiac myosin |
| 257337 | ΔN_RLC-ELP-ybbR-LA-GB1-GB1-Xmod-DocIII-Ctag | Polyprotein for applying force to the N- and C-termini of the lever arm in the RLC complex of human β-cardiac myosin, where residues of 2-22 of the RLC were deleted. |