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Structure and activity of a class II lanthipeptide from a thermophilic bacterium.

Weir E, Zhu L, van der Donk WA
bioRxiv [Preprint]. 2026 Apr 4:2026.04.02.716199. doi: 10.64898/2026.04.02.716199. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
257743pRSFDuet_His-TlaMExpression of NpuM, the lanthionine synthase, and for co-expression with the precursor peptide, TlaA WT and mutants
257745pETDuet-His-SUMO-TlaA2For expression and co-expression with the modifying enzyme in the pathway, TlaM
257746pETDuet-His-SUMO-TlaA1For expression and co-expression with the modifying enzyme in the pathway, TlaM
257747pETDuet-His-SUMO-TlaA2E6DFor expression and co-expression with the modifying enzyme in the pathway, TlaM

Antibodies from Article