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The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.

Ambrosi C, Pfaendler R, Eleftheriou K, Butz S, Recchia D, Bao X, Cardoso da Silva R, Kupfer N, Lagerwaard IM, Vlaming H, Schmolka N, Bhardwaj V, Baubec T
EMBO J. 2026 May;45(10):3430-3443. doi: 10.1038/s44318-026-00768-2. Epub 2026 Apr 10. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
260581pv9_NLS_TurboExpresses NLS-Turbo
260582pv9_Setd2_SRI_TurboIDExpresses SETD2-SRI domain fused to TurboID including flexible linker and NLS

Antibodies from Article