VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation.

Yoon PH, Docter TA, Zhang ZT, Loi K, Lopez SC, Valentin-Alvarado LE, Tuck OT, Brohawn SG, Doudna JA
Science. 2026 Sep 17;393(6817):1236-1240. doi: 10.1126/science.aei3472. Epub 2026 Sep 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
260463	pKL_633	RNP expression or purification plasmid
260482	pKL_675	Structure-guided mutant plasmid
260494	pKL_735	Structure-guided mutant plasmid
260495	pKL_736	Structure-guided mutant plasmid