A CD45 minigene restores regulated isoform expression and immune function in CD45-deficient mice: therapeutic implications for human CD45-null severe combined immunodeficiency.
Virts EL, Diago O, Raschke WC
Blood. 2003 Feb 1;101(3):849-55. doi: 10.1182/blood-2002-07-1969. Epub 2002 Sep 19.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 261735 | pVGI-0020-dC | Expresses murine CD45.1 with a deletion of the cytosolic domain such that only the 12 post-transmembrane amino acids of the cytosolic domain remain. Correct isoform expression remains intact. |