The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination.
Alvaro-Aranda L, Petitalot A, Djeghmoum Y, Panigada D, Singh JK, Ehlen A, Vugic D, Martin C, Miron S, Contreras-Perez A, Nhiri N, Boucherit V, Lafitte P, Dumoulin I, Quiles F, Rouleau E, Jacquet E, Feliubadalo L, Del Valle J, Sharan SK, Stoppa-Lyonnet D, Zinn-Justin S, Lazaro C, Caputo SM, Carreira A
Nucleic Acids Res. 2024 Jul 8;52(12):6964-6976. doi: 10.1093/nar/gkad1222.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 263544 | pAC337 | Expression MBP-RFP-tagged human BRCA2 in mammalian cells |