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ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.
Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y
Proc Natl Acad Sci U S A. 2009 Feb 17. 106(7):2200-5.
PubMed Article

Plasmids from Article

ID Plasmid  
26112PGL3-NOXA-N1
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26113PGL3-NOXA-N2
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26114pRK-ATF4
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26115pRK-ATF3
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26118pRK-ATF4 1-275
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26119pRK-ATF4 111-351
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26120pRK-ATF4 248-351
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