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The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.
Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, Xu Z
PLoS One. 2010 . 5(12):e15878.
PubMed Journal

Plasmids from Article

ID Plasmid  
28195 tdp43-EGFP construct2 Add to Cart
28196 tdp43-EGFP construct3 Add to Cart
28197 tdp43-EGFP construct4 Add to Cart
28198 tdp43-EGFP construct5 Add to Cart
28199 tdp43-EGFP construct6 Add to Cart
28200 tdp43-EGFP construct7 Add to Cart
28201 tdp43-EGFP construct8 Add to Cart
28202 tdp43-EGFP construct9 Add to Cart
28203 tdp43-EGFP construct10 Add to Cart
28204 tdp43-EGFP construct11 Add to Cart
28205 wtTDP43tdTOMATOHA Add to Cart
28206 TDP43 NOTAG1 Add to Cart
28207 TDP43 NOTAG2 Add to Cart
28208 TDP43 NOTAG3 Add to Cart
28209 TDP43 NOTAG6 Add to Cart
28210 TDP43 NOTAG11 Add to Cart
28211 miR-TDP43a Add to Cart
28212 miR-TDP43b Add to Cart

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