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The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.
Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, Xu Z
PLoS One. 2010 . 5(12):e15878.
PubMed Journal

Plasmids from Article

ID Plasmid  
28195tdp43-EGFP construct2 Add to Cart
28196tdp43-EGFP construct3 Add to Cart
28197tdp43-EGFP construct4 Add to Cart
28198tdp43-EGFP construct5 Add to Cart
28199tdp43-EGFP construct6 Add to Cart
28200tdp43-EGFP construct7 Add to Cart
28201tdp43-EGFP construct8 Add to Cart
28202tdp43-EGFP construct9 Add to Cart
28203tdp43-EGFP construct10 Add to Cart
28204tdp43-EGFP construct11 Add to Cart
28205wtTDP43tdTOMATOHA Add to Cart
28206TDP43 NOTAG1 Add to Cart
28207TDP43 NOTAG2 Add to Cart
28208TDP43 NOTAG3 Add to Cart
28209TDP43 NOTAG6 Add to Cart
28210TDP43 NOTAG11 Add to Cart
28211miR-TDP43a Add to Cart
28212miR-TDP43b Add to Cart

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