Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

An Engineered GluCl Channel for Sensitive, Consistent Neuronal Silencing by Ivermectin.
Frazier SJ, Cohen BN, Lester HA
J Biol Chem. 2013 May 29.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
47387pcDNA3.1 V5 His-TOPO-GluCl optalpha-mYFP L9'F (Opt α-GluClv2.0)allow pharmacologically induced silencing of electrical activity in CNS neurons upon exposure to the anthelmintic drug ivermectin
Loading...
47542pcDNA3.1 V5 His-TOPO-GluCl optbeta-m-YFP Y182F RSR_AAA (Opt β-Gluclv2.0)engineered receptor improves heteromeric receptor expression and sensitivity to IVM.
Loading...