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An Engineered GluCl Channel for Sensitive, Consistent Neuronal Silencing by Ivermectin.
Frazier SJ, Cohen BN, Lester HA
J Biol Chem. 2013 May 29. PubMed Article

Plasmids from Article

ID Plasmid Purpose
47387pcDNA3.1 V5 His-TOPO-GluCl optalpha-mYFP L9'F (Opt α-GluClv2.0)allow pharmacologically induced silencing of electrical activity in CNS neurons upon exposure to the anthelmintic drug ivermectin
47542pcDNA3.1 V5 His-TOPO-GluCl optbeta-m-YFP Y182F RSR_AAA (Opt β-Gluclv2.0)engineered receptor improves heteromeric receptor expression and sensitivity to IVM.

Antibodies from Article