The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder.
Burns JN, Turnage KC, Walker CA, Lieberman RL
Biochemistry. 2011 Jul 5;50(26):5824-33. doi: 10.1021/bi200231x. Epub 2011 Jun 9. PubMed Article
Burns JN, Turnage KC, Walker CA, Lieberman RL
Biochemistry. 2011 Jul 5;50(26):5824-33. doi: 10.1021/bi200231x. Epub 2011 Jun 9. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 47699 | pmalc4x_E323K_TEV | Expresses MBP myocilin olfactomedin domain fusion protein with a TEV protease recognition sequence and the mutation E323K |
| 47701 | pmalc4x_K398R_TEV | Expresses MBP myocilin olfactomedin domain fusion protein with a TEV protease recognition sequence and the mutation K398R |
| 47702 | pmalc4x_V426F_TEV | Expresses MBP myocilin olfactomedin domain fusion protein with a TEV protease recognition sequence and the mutation V426F |
| 47703 | pmalc4x_I499F_TEV | Expresses MBP myocilin olfactomedin domain fusion protein with a TEV protease recognition sequence and the mutation I499F |
| 47704 | pmalc4x_G252R_TEV | Expresses MBP myocilin olfactomedin domain fusion protein with a TEV protease recognition sequence and the mutation G252R |