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Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Ko M, An J, Bandukwala HS, Chavez L, Aijo T, Pastor WA, Segal MF, Li H, Koh KP, Lahdesmaki H, Hogan PG, Aravind L, Rao A
Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
49446FH-TET3-pEFThis plasmid expresses full-length human TET3.
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68553Myc-Idax WTThis plasmid expresses full length IDAX.
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68554Myc-Idax DBMThis plasmid expresses full length IDAX containing a DNA binding mutation.
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127895FH-TET3-CXXCmut-pEFExpresses ten-eleven-translocation 3 (TET3) containing CXXC mutation 80THQ82 to AAA
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127896FH-TET3-HxDmut-pEFExpresses ten-eleven-translocation 3 (TET3) containing HxD mutation at H1077Y and D1079A
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Antibodies from Article