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Dicer recognizes the 5' end of RNA for efficient and accurate processing.
Park JE, Heo I, Tian Y, Simanshu DK, Chang H, Jee D, Patel DJ, Kim VN
Nature. 2011 Jul 13;475(7355):201-5. doi: 10.1038/nature10198.
PubMed Journal

Plasmids from Article

ID Plasmid  
51368 pcDNA3.1-FLAG-Dicer-5'-pocket mutant Add to Cart
51369 pcDNA3.1-FLAG-Dicer-Y926F/R927A (3'-pocket mutant) Add to Cart