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AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking.
Setta-Kaffetzi N, Simpson MA, Navarini AA, Patel VM, Lu HC, Allen MH, Duckworth M, Bachelez H, Burden AD, Choon SE, Griffiths CE, Kirby B, Kolios A, Seyger MM, Prins C, Smahi A, Trembath RC, Fraternali F, Smith CH, Barker JN, Capon F
Am J Hum Genet. 2014 May 1;94(5):790-7. doi: 10.1016/j.ajhg.2014.04.005.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
58292pcDNA3.1-myc-AP1S3mammalian expression of AP1S3
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58293pcDNA3.1-myc-AP1S3 F4Cmammalian expression of AP1S3 F4C mutant
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58294pcDNA3.1-myc-AP1S3 R33Wmammalian expression of AP1S3 R33W mutant
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Antibodies from Article