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Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer.
Fawdar S, Trotter EW, Li Y, Stephenson NL, Hanke F, Marusiak AA, Edwards ZC, Ientile S, Waszkowycz B, Miller CJ, Brognard J
Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12426-31. doi: 10.1073/pnas.1305207110. Epub 2013 Jul 8.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
60531pENTR221-FGFR4Entry vector for human FGFR4
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60532pDONR223 PAK5Donor vector for human Pak5
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60533pDONR223 PAK5 P50LDonor vector for human Pak5 P50L mutant
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60534pDONR223 PAK5 P76TDonor vector for human Pak5 P76T mutant
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60535pDONR223 PAK5 S312CDonor vector for human Pak5 S312C mutant
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60536pDONR223 PAK5 V463LDonor vector for human Pak5 V463L mutant
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60537pDONR223 PAK5 T538NDonor vector for human Pak5 T538N mutant
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60538pDONR223 PAK5 S573NDonor vector for human Pak5 S573N mutant
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60539pDONR223 PAK5 V593IDonor vector for human Pak5 V593I mutant
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60540pDONR221 MLK1Donor vector for human MLK1
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60541pDONR221 MLK1 E179KDonor vector for human MLK1 E179K mutant
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60542pDONR221 MLK1 D294ADonor vector for human MLK1 D294A mutant
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Recombinant Antibodies from Article