mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.
Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM
Curr Biol. 2006 Sep 19;16(18):1865-70. doi: 10.1016/j.cub.2006.08.001. Epub 2006 Aug 17.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 12570 | pMSCV-TAP | |
| 12575 | pMSCV-TAP mLST8 (aka: GbL) | |
| 12576 | pMSCV mSin1.1 myc | |
| 12577 | pMSCV mSin1.2 myc | |
| 12578 | pMSCV mSin1.4 myc | |
| 12579 | pMSCV mSin1.5 myc | |
| 12580 | pMSCV mLST8 myc (aka: GbL-myc) | |
| 12581 | pMSCV tubulin myc | |
| 12582 | pMSCV mSin1.1 HA | |
| 12583 | pMSCV mSin1.2 HA | |
| 12587 | pMSCV-TAP Raptor | |
| 13483 | mSin1 shRNA #1 | |
| 13484 | mSin1 shRNA #2 |