The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.
Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, Chan FK, Wu H
Cell. 2012 Jul 20;150(2):339-50. doi: 10.1016/j.cell.2012.06.019. PubMed Article
Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, Chan FK, Wu H
Cell. 2012 Jul 20;150(2):339-50. doi: 10.1016/j.cell.2012.06.019. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 61367 | pEYFP-N1-hRIP3-FL G457D | Expresses Human full length RIPK3 with G457Dmutation in the mammalian cells |
| 61368 | pEYFP-N1-hRIP3-FL VV458/460PP | Expresses Human full length RIPK3 with A458P/V460P mutation in the mammalian cells |
| 61369 | pEYFP-N1-hRIP3-FL N464D | Expresses Human full length RIPK3 with N464D mutation in the mammalian cells |
| 61377 | pEYFP-N1-hRIP3-FL V458P | Expresses Human full length RIPK3 with V458P mutation in the mammalian cells |
| 61379 | pEYFP-N1-hRIP3-FL V460P | Expresses Human full length RIPK3 with V460P mutation in the mammalian cells |
| 61380 | pEGFP-N1-hRIP1-FL I539P | Expresses Human full length RIPK1with I539P mutation in the mammalian cells |
| 61381 | pEGFP-N1-hRIP1-FL I541P | Expresses Human full length RIPK1 with I541P mutation in the mammalian cells |
| 61386 | pRIP3-mCherry | Expresses RIP3-mCherry in mammalian cells |