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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.
Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, Chan FK, Wu H
Cell. 2012 Jul 20;150(2):339-50. doi: 10.1016/j.cell.2012.06.019.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
61367pEYFP-N1-hRIP3-FL G457DExpresses Human full length RIPK3 with G457Dmutation in the mammalian cells
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61368pEYFP-N1-hRIP3-FL VV458/460PPExpresses Human full length RIPK3 with A458P/V460P mutation in the mammalian cells
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61369pEYFP-N1-hRIP3-FL N464DExpresses Human full length RIPK3 with N464D mutation in the mammalian cells
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61377pEYFP-N1-hRIP3-FL V458PExpresses Human full length RIPK3 with V458P mutation in the mammalian cells
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61379pEYFP-N1-hRIP3-FL V460PExpresses Human full length RIPK3 with V460P mutation in the mammalian cells
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61380pEGFP-N1-hRIP1-FL I539PExpresses Human full length RIPK1with I539P mutation in the mammalian cells
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61381pEGFP-N1-hRIP1-FL I541PExpresses Human full length RIPK1 with I541P mutation in the mammalian cells
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61386pRIP3-mCherryExpresses RIP3-mCherry in mammalian cells
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Recombinant Antibodies from Article