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Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC
Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
62511pcw107Gateway Expression Vector
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64602Kras (G12V)-pcw107when used to produce lentivirus, express physiological levels of insert
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64603Hras (G12V)-pcw107when used to produce lentivirus, express physiological levels of insert
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64604MEK1 (S218D,S222D)-pcw107when used to produce lentivirus, express physiological levels of insert
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64605myr-FLAG-PIK3CA-pcw107when used to produce lentivirus, express physiological levels of insert
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64606myr-FLAG-AKT1-pcw107when used to produce lentivirus, express physiological levels of insert
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64607FLAG-Rheb (Q64L)-pcw107when used to produce lentivirus, express physiological levels of insert
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64608IKKalpha (S176E,S180E)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64609FLAG-IKKbeta (S177E,S181E)-pcw107when used to produce lentivirus, express physiological levels of insert
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64610JAK2 (V617F)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64611Stat3 (A662C,N664C,V667L)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64612beta-catenin (S33A, S37A, T41A, S45A)-pcw107 when used to produce lentivirus, express physiological levels of insert
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64613beta-catenin (S33A, S37A, T41A, S45A)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64614GSK3beta (K85A)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64615beta-catenin (S33Y)-pcw107when used to produce lentivirus, express physiological levels of insert
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64616beta-catenin (S33Y)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64617JNK2 WT O/E (MAPK9)-pcw107-V5 when used to produce lentivirus, express physiological levels of insert
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64618FLAG-Mkk7-JNK2 fusion-pcw107 Mkk7-JNK2 fusion - barcoded activating construct of JNK pathway
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64619MEK5 DD(S311D,T315D)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64620myr-FLAG-MEK5-pcw107when used to produce lentivirus, express physiological levels of insert
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64621Notch1 intracellular domain-pcw107 when used to produce lentivirus, express physiological levels of insert
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64622Notch1 intracellular domain-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64623Notch3 intracellular domain-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64624p38 WT O/E (MAPK14)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64625FLAG-MKK6 (S207E,T211E)-pcw107 when used to produce lentivirus, express physiological levels of insert
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64626Gli2 truncation-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64627SmoM2 (W535L)-pcw107 when used to produce lentivirus, express physiological levels of insert
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64628SmoM2 (W535L)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64629TGFbetaR1 (T204D)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64630BCL2-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64631BCL-XL-pcw107-V5 when used to produce lentivirus, express physiological levels of insert
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64632Caspase-8 (C360A)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64633Caspase-3 (C163A)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64634ERalpha (Y537S mutant)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64635AR-V7-pcw107 when used to produce lentivirus, express physiological levels of insert
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64636AR-V7-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64637FLAG-YAP2 (8SA)-pcw107when used to produce lentivirus, express physiological levels of insert
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64638p53 (dominant negative R175H mutant)-pcw107-V5 3rd generation lentiviral transfer plasmid. When used to produce lentivirus, express physiological levels of insert
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64639HRas (G12V, E37G)-pcw107 when used to produce lentivirus, express physiological levels of insert
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64640HRas (G12V, E37G)-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64641Rgl2-CAAX-pcw107-V5when used to produce lentivirus, express physiological levels of insert
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64642RalA (G23V)(mature peptide)-pcw107 when used to produce lentivirus, express physiological levels of insert
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64643RalA (G23V)(mature peptide)-pcw107-V5 when used to produce lentivirus, express physiological levels of insert
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64644RalA (G23V)( full )-pcw107 when used to produce lentivirus, express physiological levels of insert
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64645RalA (G23V)( full )-pcw107-V5(control) when used to produce lentivirus, express physiological levels of insert
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64646HcRed-pcw107 when used to produce lentivirus, express physiological levels of insert
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64647HcRed-pcw107-V5(control) when used to produce lentivirus, express physiological levels of insert
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64648Luciferase-pcw107 (control) when used to produce lentivirus, express physiological levels of insert
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64649Luciferase-pcw107-V5(control) when used to produce lentivirus, express physiological levels of insert
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64650MEK1-pcw107-V5(control) when used to produce lentivirus, express physiological levels of insert
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