Addgene: Evaluation of loss of function as an explanation for SPG4-based hereditary spastic paraplegia.

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Peter Baas
Solowska et al

Evaluation of loss of function as an explanation for SPG4-based hereditary spastic paraplegia.
Solowska JM, Garbern JY, Baas PW
Hum Mol Genet. 2010 Jul 15;19(14):2767-79. doi: 10.1093/hmg/ddq177. Epub 2010 Apr 29. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
87715	pCMV-Tag 3A/myc-M1E112K	Expresses myc-M1E112K spastin isoform in mammalian cells
87716	pCMV-Tag 3A/myc-M1L195V	Expresses myc-M1L195V spastin isoform in mammalian cells
87717	pCMV-Tag 3A/myc-M1S44L	Expresses myc-M1S44L spastin isoform in mammalian cells
87718	pCMV-Tag 3A/myc-M1S46X	Expresses myc-M1S46X spastin isoform in mammalian cells
87719	pCMV-Tag 3A/WT myc-M1	Expresses WT myc-M1 spastin isoform in mammalian cells
87720	pCMV-Tag 3B/myc-M87E112K	Expresses myc-M87E112K spastin isoform in mammalian cells
87721	pCMV-Tag 3B/myc-M87L195V	Expresses myc-M87L195V spastin isoform in mammalian cells
87722	pCMV-Tag 3B/WT myc-M87	Expresses WT myc-M87 spastin isoform in mammalian cells
87723	pCMV-Tag/E112K with 5'UTR	Expresses E112K spastin M1 and M87 in mammalian cells
87724	pCMV-Tag/E112K without 5'UTR	Expresses E112K spastin M1 and M87 in mammalian cells
87725	pCMV-Tag/L195V with 5'UTR	Expresses L195V spastin M1 and M87 in mammalian cells
87726	pCMV-Tag/L195V without 5'UTR	Expresses L195V spastin M1 and M87 in mammalian cells
87727	pCMV-Tag/S44L with 5'UTR	Expresses S44L spastin M1 and M87 in mammalian cells
87728	pCMV-Tag/S44L without 5'UTR	Expresses S44L spastin M1 and M87 in mammalian cells
87729	pCMV-Tag/S46X with 5'UTR	Expresses S46X spastin M1 and M87 in mammalian cells
87730	pCMV-Tag/S46X without 5'UTR	Expresses S46X spastin M1 and M87 in mammalian cells
87731	pCMV-Tag/WT SPAST with 5'UTR	Expresses WT spastin M1 and M87 in mammalian cells
87732	pCMV-Tag/WT SPAST without 5'UTR	Expresses WT spastin M1 and M87 in mammalian cells

Antibodies from Article