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Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow.
Zeng L, Zampetaki A, Margariti A, Pepe AE, Alam S, Martin D, Xiao Q, Wang W, Jin ZG, Cockerill G, Mori K, Li YS, Hu Y, Chien S, Xu Q
Proc Natl Acad Sci U S A. 2009 May 19;106(20):8326-31. doi: 10.1073/pnas.0903197106. Epub 2009 May 1.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
63677Ad-Flag-XBP1uAdenoviral vector for XBP1u expression
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63678Ad-Flag-XBP1sAdenoviral vector for XBP1s expression
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63679pShuttle-Flag-XBP1uAdenoviral shuttle vector for XBP1u expression
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63680pCMV5-Flag-XBP1sMammalian expression of Flag tagged XBP1s
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