We narrowed to 22,595 results for: CAR

1. pRRL-MND-hCard11 delta e3-T2A-GFP

   Plasmid

   #163770

   Purpose

   Expression of CARD domain variant with a deletion of exon 3

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Del exon 3

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pRRL-MND-hCard11 K69L-T2A-GFP

   Plasmid

   #163781

   Purpose

   Expression of K69L CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   K69L

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pRRL-MND-hCard11 R35K-T2A-GFP

   Plasmid

   #163776

   Purpose

   Expression of R35K CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   R35K

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pRRL-MND-hCard11 K41Q-T2A-GFP

   Plasmid

   #163777

   Purpose

   Expression of K41Q CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   K41Q

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pRRL-MND-hCard11 K41L-T2A-GFP

   Plasmid

   #163778

   Purpose

   Expression of K41L CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   K41L

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pRRL-MND-hCard11 K69Q-T2A-GFP

   Plasmid

   #163780

   Purpose

   Expression of K69Q CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   K69Q

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pRRL-MND-hCard11 R72K-T2A-GFP

   Plasmid

   #163785

   Purpose

   Expression of R72K CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   R72K

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pRRL-MND-hCard11 K69R-T2A-GFP

   Plasmid

   #163782

   Purpose

   Expression of K69R CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   K69R

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pRRL-MND-hCard11 R35L-T2A-GFP

   Plasmid

   #163775

   Purpose

   Expression of R35L CARD domain variant

   Depositor

   Richard James

   Article

   Meitlis et al Am J Hum Genet. 2020 Nov 12. pii: S0002-

   Insert

   CARD11 (CARD11 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   R35L

   Promoter

   MND

   Available since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pcDNA3.1 6A NLRP1 UPA-CARD-FLAG E1397R

    Plasmid

    #163982

    Purpose

    Mammalian expression vector encoding human NLRP1 UPA-CARD (filament-deficient mutant) with a C-terminal FLAG tag

    Depositor

    Hao Wu

    Article

    Robert Hollingsworth et al Nat Commun. 2021 Jan 8;12(1):189. doi: 1

    Insert

    NLRP1 UPA-CARD (NLRP1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    E1397R

    Promoter

    Available since

    Jan. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pcDNA3.1 6A NLRP1 UPA-CARD-FLAG R1392E

    Plasmid

    #163981

    Purpose

    Mammalian expression vector encoding human NLRP1 UPA-CARD (filament-deficient mutant) with a C-terminal FLAG tag

    Depositor

    Hao Wu

    Article

    Robert Hollingsworth et al Nat Commun. 2021 Jan 8;12(1):189. doi: 1

    Insert

    NLRP1 UPA-CARD (NLRP1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    R1392E

    Promoter

    Available since

    Jan. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pcDNA3.1 6A NLRP1 UPA-CARD-FLAG R1386E

    Plasmid

    #163980

    Purpose

    Mammalian expression vector encoding human NLRP1 UPA-CARD (filament-deficient mutant) with a C-terminal FLAG tag

    Depositor

    Hao Wu

    Article

    Robert Hollingsworth et al Nat Commun. 2021 Jan 8;12(1):189. doi: 1

    Insert

    NLRP1 UPA-CARD (NLRP1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    R1386E

    Promoter

    Available since

    Jan. 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. AAV-Synapsin-mScarlet-3XNLS-optoNES-WPRE

    Plasmid

    #159948

    Purpose

    optical regulation of nuclear export

    Depositor

    Michael Courtney

    Article

    Li et al Nat Commun. 2020 Oct 9;11(1):5107. doi:

    Insert

    mScarlet-3XNLS-optoNES
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    synthetic

    Promoter

    hSyn1

    Available since

    Oct. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. AAV-Synapsin-NLS-mScarlet-optoNES-WPRE

    Plasmid

    #159943

    Purpose

    optical regulation of nuclear export

    Depositor

    Michael Courtney

    Article

    Li et al Nat Commun. 2020 Oct 9;11(1):5107. doi:

    Insert

    NLS-mScarlet-optoNES
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    synthetic

    Promoter

    hSyn1

    Available since

    Oct. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pDY0181 Cargo EGFP with AttP Bxb1 site (Parent minicircle)

    Plasmid

    #179115

    Purpose

    Cargo EGFP with AttP Bxb1 site (Parent minicircle)

    Depositor

    Jonathan Gootenberg, Omar Abudayyeh

    Article

    Yarnall et al Nat Biotechnol. 2022 Nov 24. doi: 10.103

    Insert

    Cargo EGFP with AttP Bxb1 site
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. AAVS1-Puro CAG CLTX-NKG2D-2B4-CD3z CAR

    Plasmid

    #157744

    Purpose

    knock CLTX-NKG2D-2B4-CD3z CAR into AAVS1 safe harbor locus for constitutive expression

    Depositor

    Xiaoping Bao

    Article

    Chang et al Cell Rep. 2022 Jul 19;40(3):111128. doi:

    Insert

    chlorotoxin containing chimeric antigen receptor targeting glioblastoma
    

    Use

    CRISPR, Synthetic Biology, and TALEN

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAG

    Available since

    Jan. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pAAV-hSyn-DIO {mCAR}off-{DTR-GFP}on-WPRE

    Plasmid

    #111395

    Purpose

    AAV vector with hSynapsin promoter, Cre-OFF mCAR (for efficient CAV-2 infection), Cre-ON DTR-EGFP (diphtheria toxin receptor for cell ablation)

    Depositor

    Adam Kepecs

    Article

    Li et al Neuron. 2018 Jun 6;98(5):905-917.e5. doi

    Inserts

    mCAR (Cxadr Mouse)
    DTR-EGFP
    

    Use

    AAV

    Tags

    EGFP and Myc

    Expression

    Mammalian

    Mutation

    Promoter

    hSynapsin

    Available since

    June 8, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pAAV-hSyn-DIO {hCAR}off-{hM4Di-mCherry}on-W3SL

    Plasmid

    #111397

    Purpose

    AAV vector with hSynapsin promoter, Cre-OFF hCAR (for efficient CAV-2 infection), Cre-ON hM4Di-mCherry (Gi-coupled DREADD for neuronal silencing), W3SL cassette (for maximize cloning capacity)

    Depositor

    Adam Kepecs

    Article

    Li et al Neuron. 2018 Jun 6;98(5):905-917.e5. doi

    Inserts

    hCAR (CXADR Human)
    hM4Di-mCherry
    

    Use

    AAV

    Tags

    Myc and mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    hSynapsin

    Available since

    June 6, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pCMV-T7-SpCas9-BPNLS(SV40)-3xFLAG-P2A-mScarlet (MNW001)

    Plasmid

    #174091

    Purpose

    CMV and T7 promoter expression plasmid for human codon optimized SpCas9 with a C-terminal bi-partite NLS, 3x flag tag, and P2A-mScarlet

    Depositor

    Benjamin Kleinstiver

    Insert

    human codon optimized SpCas9 with BPNLS-3xFLAG-P2A-mScarlet
    

    Use

    In vitro transcription; t7 promoter

    Tags

    BPNLS-3xFLAG-P2A-mScarlet

    Expression

    Mammalian

    Mutation

    Promoter

    pCMV and T7

    Available since

    Sept. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pHR-OFF VIPER CAR (anti-CD19)-candidate design(d+i)

    Plasmid

    #192123

    Purpose

    Lentiviral deliviery of OFF VIPER CAR (anti-CD19)-candidate design(d+i)

    Depositor

    Wilson Wong

    Article

    Li et al Cancer Cell. 2022 Aug 26. pii: S1535-610

    Insert

    pEF1a-anti-CD19scFV_CD28__41BB_peptide_P2A_DAP10_41BB_NS3(s139a)_CD3z-mCherry
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge