We narrowed to 8,211 results for: aav

1. pAAV-EFS-TadA8e-SaKKH-U6-sgRNA scaffold

   Plasmid

   #226935

   Purpose

   Encoding SaKKHABE8e and sgRNA cassette on a single AAV

   Depositor

   Yuxuan Guo

   Article

   Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

   Insert

   TadA8e, nSaKKHCas9
   

   Use

   AAV

   Promoter

   EFS

   Available Since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pC131: pAAV.CMV-CasRx-VEGFA sgRNA array

   Plasmid

   #203444

   Purpose

   Plasmid expressing active RfxCas13d with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   RfxCas13d
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pM150: pAAV.CMV-Cas13e-VEGFA sgRNA array

   Plasmid

   #203448

   Purpose

   Plasmid expressing active Cas13e with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pM156: pAAV.CMV-Cas13e (GenScript CO)-VEGFA sgRNA

   Plasmid

   #203452

   Purpose

   Plasmid expressing active and codon optimised Cas13e with VEGFA gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. AAVS1-TRE3G-SOX2-3xHA-P2A-tagBFP

   Plasmid

   #163701

   Purpose

   Dox-inducible SOX2-3xHA HDR knock-in cassette into the AAVS1 locus with a tagBFP fluorescent marker linked by a self-cleaving P2A peptide.

   Depositor

   Jennifer Mitchell

   Article

   Abatti et al Nucleic Acids Res. 2023 Sep 22:gkad734.

   Inserts

   SOX2-3xHA-P2A-tagBFP (SOX2 Human)
   rtTA
   T2-sgRNA
   

   Use

   AAV and CRISPR

   Tags

   3x-HA and P2A-tagBFP

   Expression

   Mammalian

   Promoter

   CAG and TRE3G

   Available Since

   Oct. 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-U6-sgRev-erba-hSyn-mCherry-KASH

   Plasmid

   #223226

   Purpose

   guideRNA targeting the mouse Rev-erb alpha (Nr1d1)

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   Nr1d1 (Nr1d1 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAV-TRE-dSaCas9-NLS-3xHA-3xSunTag_bGHpA

   Plasmid

   #177344

   Purpose

   AAV expression of a catalytically inactive SaCas9 (dSaCas9) fused with three copies of SunTag sequence from doxycycine-inducible promoter

   Depositor

   Naoki Yamamoto

   Article

   Yamamoto et al Research Square [Preprint] 2021. doi: 10

   Insert

   dead hSaCas9
   

   Use

   AAV and CRISPR

   Tags

   3x GCN4 peptide, 3xHA, and NLS

   Expression

   Mammalian

   Mutation

   D10A, N580A

   Promoter

   Tetracycline-dependent promoters

   Available Since

   Sept. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. AAV-CMV-dSaCas9-NLS-3xHA-3xSunTag_bGHpA

   Plasmid

   #177342

   Purpose

   AAV expression of a catalytically inactive SaCas9 (dSaCas9) fused with three copies of SunTag sequence

   Depositor

   Naoki Yamamoto

   Article

   Yamamoto et al Research Square [Preprint] 2021. doi: 10

   Insert

   dead hSaCas9
   

   Use

   AAV and CRISPR

   Tags

   3x GCN4 peptide, 3xHA, and NLS

   Expression

   Mammalian

   Mutation

   D10A, N580A

   Promoter

   CMV

   Available Since

   Sept. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pBK1297-AAV-EFSNC-dCjCas9-HP1b(79-173)

   Plasmid

   #223142

   Purpose

   Expression of truncated HP1b with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 79-173

   Promoter

   EF1a

   Available Since

   Aug. 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBK1295-AAV-EFSNC-dCjCas9-HP1a(72-177)

    Plasmid

    #223140

    Purpose

    Expression of truncated HP1a with dCjCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1a (CBX5 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 72-177

    Promoter

    EF1a

    Available Since

    Aug. 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pBK1305-AAV-EFSNC-dSaCas9-HP1a(72-177)

    Plasmid

    #223150

    Purpose

    Expression of truncated HP1a with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1a (CBX5 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 72-177

    Promoter

    EF1a

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pBK1307-AAV-EFSNC-dSaCas9-HP1b(79-173)

    Plasmid

    #223152

    Purpose

    Expression of truncated HP1b with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1b (CBX1 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 79-173

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pBK2043-AAV-2xSp1-2xNFkB-EFSNC-dSaCas9

    Plasmid

    #223163

    Purpose

    2nd gen. AAV backbone for dSaCas9 (endonuclease dead Cas9 from Staphylococcus aureus) and Sa-gRNA Scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Type

    Empty backbone

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 204-310 (MECP2)

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. AAV-hSyn-ZipT-2A-IvfChr (citrine, KV2.1)

    Plasmid

    #221619

    Purpose

    A recombinant AAV2 plasmid encoding the ZipACR I151T mutant with soma targeting with KV2.1 motif and membrane expression enhanced vfChrimson-Citrine with soma targeting KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    ZipACR (I151V)KV2.1-2A-IvfChr-citrine-Kv2.1
    

    Use

    AAV

    Mutation

    ZipACR (I151T) with soma targeting, vfChrimson w…

    Promoter

    Human Synapsin

    Available Since

    Aug. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV-hSyn-ZipT-2A-IvfChr (mCherry, KV2.1)

    Plasmid

    #221621

    Purpose

    A recombinant AAV2 plasmid encoding the ZipACR I151T mutant with soma targeting with KV2.1 motif and membrane expression enhanced vfChrimson-mCHerry with soma targeting KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    ZipACR (I151V)KV2.1-2A-IvfChr-mCherry-Kv2.1
    

    Use

    AAV

    Mutation

    ZipACR (I151T) with soma targeting, vfChrimson w…

    Promoter

    Human Synapsin

    Available Since

    Aug. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. AAV-hSyn-ZipV-2A-IvfChr (citrine, KV2.1)

    Plasmid

    #221618

    Purpose

    A recombinant AAV2 plasmid encoding the ZipACR I151V mutant with soma targeting with KV2.1 motif and membrane expression enhanced vfChrimson-Citrine with soma targeting KV2.1 motif.

    Depositor

    John Lin

    Article

    Mermet-Joret et al eLife 2023 12:RP90327

    Insert

    ZipACR (I151V)KV2.1-2A-IvfChr-citrine-Kv2.1
    

    Use

    AAV

    Mutation

    ZipACR (I151V) with soma targeting, vfChrimson w…

    Promoter

    Human Synapsin

    Available Since

    Aug. 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. AAVS1-Puro cTnT CCND2-T2A-ChloC

    Plasmid

    #179841

    Purpose

    donor plasmid for cardiac-specific CCND2-T2A-Chloc expression in human cells

    Depositor

    Xiaoping Bao

    Article

    Joshi et al Cells. 2022 Mar 10;11(6). pii: cells1106

    Insert

    CCND2 (CCND2 Human)
    

    Use

    CRISPR and TALEN; Donor plasmid

    Tags

    chloride-conducting ChR (ChloC)

    Expression

    Mammalian

    Promoter

    Troponin T promoter

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. AAVS1-Puro cTnT CCND2-T2A-iChloC

    Plasmid

    #179842

    Purpose

    donor plasmid for cardiac-specific CCND2-T2A-iChloc expression in human cells

    Depositor

    Xiaoping Bao

    Article

    Joshi et al Cells. 2022 Mar 10;11(6). pii: cells1106

    Insert

    CCND2 (CCND2 Human)
    

    Use

    CRISPR and TALEN; Donor plasmid

    Tags

    improved chloride-conducting ChR (iChloC)

    Expression

    Mammalian

    Promoter

    Troponin T promoter

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. AAVS1-Puro cTnT CCND2-T2A-luciferase

    Plasmid

    #179844

    Purpose

    donor plasmid for cardiac-specific CCND2-T2A-luciferase expression in human cells

    Depositor

    Xiaoping Bao

    Article

    Joshi et al Cells. 2022 Mar 10;11(6). pii: cells1106

    Insert

    CCND2 (CCND2 Human)
    

    Use

    CRISPR, Luciferase, and TALEN ; Donor plasmid

    Tags

    luciferase

    Expression

    Mammalian

    Promoter

    Troponin T promoter

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. AiP1921 - pAAV-AiE2447m-SYFP2-WPRE-BGHpA

    Plasmid

    #214581

    Purpose

    AiE2447m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

    Depositor

    Allen Institute for Brain Science, Bosiljka Tasic

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minBG

    Available Since

    June 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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