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integrin beta6 777T pBabe puro

Plasmid

#13583

Depositor

Dean Sheppard

Article

Morris et al Nature. 2003 Mar 13. 422(6928):169-73.

Insert

integrin beta 6 777T (ITGB6 Human)

Use

Retroviral

Expression

Mammalian

Mutation

777T. Lacks last 11 amino acids of cytoplasmic do…

Available Since

Jan. 8, 2007

Availability

Academic Institutions and Nonprofits only
GFP-RanV19 E1RA2

Plasmid

#118317

Purpose

Expression of human Ran

Depositor

Philip Stork

Article

Liu et al Mol Cell Biol. 2010 Aug;30(16):3956-69.

Inserts

RanV19 (RAN Human)
EPac1RA2 (RAPGEF3, RAPGEF4 Human)

Tags

GFP

Expression

Mammalian

Mutation

in-frame insertion of RanV19 into GFPEpac1RA2 and…

Available Since

Nov. 12, 2018

Availability

Academic Institutions and Nonprofits only

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pCAG mFoxg1-GFP T271E

Plasmid

#73057

Purpose

C-terminal GFP fusion of Mouse Foxg1 T271E

Depositor

Joseph Gleeson

Article

Baek et al Nat Med. 2015 Dec;21(12):1445-54. doi: 1

Insert

Foxg1 (Foxg1 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

T271E

Available Since

March 11, 2016

Availability

Academic Institutions and Nonprofits only

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pCAG mFoxg1-GFP T271A

Plasmid

#73047

Purpose

C-terminal fusion of gfp Mouse Foxg1 T271A

Depositor

Joseph Gleeson

Article

Baek et al Nat Med. 2015 Dec;21(12):1445-54. doi: 1

Insert

Foxg1 (Foxg1 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

T271A

Promoter

CAG

Available Since

March 11, 2016

Availability

Academic Institutions and Nonprofits only

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pU6-crRNA(TBK1)

Plasmid

#109322

Purpose

AAV vector expressing crRNA for AsCpf1 (RR variant) targeting human TBK1

Depositor

Feng Zhang

Article

Tekin et al Nat Biomed Eng. 2018 Jul;2(7):540-554. d

Insert

mCherry-KASH (TBK1 Human)

Use

AAV

Promoter

hSyn

Available Since

April 30, 2018

Availability

Academic Institutions and Nonprofits only

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Rb-379-928Δ703-737-pGex2T

Plasmid

#21933

Depositor

William Kaelin

Article

Kaelin et al Cell. 1991 Feb 8. 64(3):521-32.

Insert

Rb (RB1 Human)

Tags

GST

Expression

Bacterial

Mutation

deletion mutant ORF contains aa 379-928D703-737 o…

Available Since

Sept. 30, 2009

Availability

Academic Institutions and Nonprofits only

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pDEST27-GST-ATXN1 FL(84Q)-S776A

Plasmid

#21758

Depositor

Huda Zoghbi

Article

Lim et al Nature. 2008 Apr 10. 452(7188):713-8.

Insert

Ataxin-1 (ATXN1 Human)

Tags

GST

Expression

Mammalian

Mutation

insert contains a stretch of 84 Q(Glutamines) and…

Promoter

CMV

Available Since

July 22, 2014

Availability

Academic Institutions and Nonprofits only
pDEST27-GST-ATXN1 FL(30Q)-S776A

Plasmid

#21756

Depositor

Huda Zoghbi

Article

Lim et al Nature. 2008 Apr 10. 452(7188):713-8.

Insert

Ataxin-1 (ATXN1 Human)

Tags

GST

Expression

Mammalian

Mutation

insert contains a stretch of 32 amino acids (30 Q…

Promoter

CMV

Available Since

July 22, 2014

Availability

Academic Institutions and Nonprofits only
Rb-379-928Δ738-775-pGex2T

Plasmid

#21783

Depositor

William Kaelin

Article

Kaelin et al Cell. 1991 Feb 8. 64(3):521-32.

Insert

Rb (RB1 Human)

Tags

GST

Expression

Bacterial

Mutation

deletion mutant ORF contains aa 379-928D737-774 o…

Available Since

Sept. 30, 2009

Availability

Academic Institutions and Nonprofits only

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pUltra BCR-ABL V468F

Plasmid

#210435

Purpose

Lentiviral expression of BCR-ABL V468F

Depositor

Justin Pritchard

Article

Sokirniy et al Genome Med. 2026

Insert

BCR-ABL (ABL1, BCR Human)

Use

Lentiviral

Tags

EGFP-P2A

Mutation

V468F

Available Since

April 30, 2026

Availability

Academic Institutions and Nonprofits only

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pET28a_6xHis-thrombin-SUMO-HsTNRC6B(599-683)-3xHA

Plasmid

#254374

Purpose

Expression of TNRC6B fragment for protein purification

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human TNRC6B (TNRC6B Human)

Tags

3xHA and 6xHis-thrombin-SUMO

Expression

Bacterial

Mutation

Fragment consisting of residues 599-683

Promoter

T7

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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pET28a_6xHis-thrombin-SUMO-HsTNRC6B(599-683)-3xFLAG

Plasmid

#254375

Purpose

Expression of TNRC6B fragment for protein purification

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human TNRC6B (TNRC6B Human)

Tags

3xFLAG and 6xHis-thrombin-SUMO

Expression

Bacterial

Mutation

Fragment consisting of residues 599-683

Promoter

T7

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA3.3_3xFLAG-SUMO_Eu1-HsAGO2(F491A)

Plasmid

#254376

Purpose

Expression of AGO for protein purification

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human Argonaute2 (AGO2 Human)

Tags

3xFLAG-SUMO(Eu1)

Expression

Mammalian

Mutation

F491A

Promoter

CMV

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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pcDNA3.3_3xFLAG-SUMO_Eu1-HsAGO2(K493A)

Plasmid

#254377

Purpose

Expression of AGO for protein purification

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human Argonaute2 (AGO2 Human)

Tags

3xFLAG-SUMO(Eu1)

Expression

Mammalian

Mutation

K493A

Promoter

CMV

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(337-343A)

Plasmid

#254361

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

Replace residues 337-343 with alanines

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(R1345A, R1348A, R1350A)

Plasmid

#254365

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

R1345A, R1348A, R1350A

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(R1345E, R1348E, R1350E)

Plasmid

#254366

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

R1345E, R1348E, R1350E

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(H395E, H401E, R404E)

Plasmid

#254369

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

H395E, H401E, R404E

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(mono)

Plasmid

#254354

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

Duplicate residues 222-273 within 228-229, flanke…

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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piggyBac_Tet-On_HsZSWIM8(VHL-box)

Plasmid

#254357

Purpose

Expression of ZSWIM8 to assay in-cell microRNA stability

Depositor

David Bartel

Article

Farnung et al Nature. 2026 Apr;652(8110):784-793. doi:

Insert

Human ZSWIM8 (KIAA0913 Human)

Expression

Mammalian

Mutation

Replace residues 96-102 with RLDIVRS

Promoter

TRE3G

Available Since

April 17, 2026

Availability

Academic Institutions and Nonprofits only

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