Addgene

We narrowed to 761 results for: KO

Showing: 701 - 720 of 761 results

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pCAG-eSpCas9-2A-GFP-sgRNA-RDH11

Plasmid

#161924

Purpose

To generate RDH11 KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against RDH11 exon 2.

Depositor

Sébastien Britton

Article

Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

Insert

sgRNA targeting RDH11 exon 2

Use

CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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AiP12039 - pAAV-3xSP10ins-AiE0354h-minRho-SYFP2-WPRE3-BGHpA (Alias: CN2039)

Plasmid

#208401

Purpose

AiE0354h is an enhancer sequence designed to drive AAV-mediated transgene expression in Vip+ cortical interneurons

Depositor

Jonathan Ting, The Allen Institute for Brain Science

Article

Lee et al Science. 2023 Oct 13;382(6667):eadf6484.

Insert

SYFP2

Use

AAV and Synthetic Biology

Tags

Expression

Mammalian

Mutation

Promoter

eHGT_354h (enhancer)

Available since

Jan. 10, 2024

Availability

Academic Institutions and Nonprofits only

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MG1655 Z1 malE

Bacterial Strain

#65915

Purpose

E. coli MG1655 Z1 host that produces constitutive levels of TetR, LacI and AraC off of the chromosome with additional malE KO

Depositor

Keith Tyo

Article

Sekar et al PLoS One. 2016 Feb 22;11(2):e0149746. do

Bacterial Resistance

None

Available since

March 1, 2016

Availability

Academic Institutions and Nonprofits only
MG1655 Z1 malE clpA

Bacterial Strain

#65918

Purpose

E. coli MG1655 Z1 host that produces constitutive levels of TetR, LacI and AraC off of the chromosome with additional malE, clpA KO

Depositor

Keith Tyo

Article

Sekar et al PLoS One. 2016 Feb 22;11(2):e0149746. do

Bacterial Resistance

None

Available since

March 1, 2016

Availability

Academic Institutions and Nonprofits only
MG1655 Z1 malE aat

Bacterial Strain

#65917

Purpose

E. coli MG1655 Z1 host that produces constitutive levels of TetR, LacI and AraC off of the chromosome with additional malE, aat KO

Depositor

Keith Tyo

Article

Sekar et al PLoS One. 2016 Feb 22;11(2):e0149746. do

Bacterial Resistance

None

Available since

March 1, 2016

Availability

Academic Institutions and Nonprofits only
AV04

Bacterial Strain

#115926

Purpose

Expression of dCas9 gene under the control of a Ptet promoter in the E. coli chromosome

Depositor

David Bikard

Article

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

Bacterial Resistance

None

Available since

March 26, 2019

Availability

Academic Institutions and Nonprofits only
LC-E18

Bacterial Strain

#115924

Purpose

Expression of dCas9 gene under the control of a Ptet promoter in the E. coli chromosome

Depositor

David Bikard

Article

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

Bacterial Resistance

None

Available since

March 26, 2019

Availability

Academic Institutions and Nonprofits only
MG1655 tnaA-

Bacterial Strain

#228513

Purpose

Indole-responsive Phage Infection Assay using LARP and T7 Phage with gp1 knock-out

Depositor

Timothy Whitehead

Article

Baumer et al ACS Synth Biol. 2024 Dec 20;13(12):4165-

Bacterial Resistance

None

Available since

Feb. 7, 2025

Availability

Academic Institutions and Nonprofits only
Mouse Chromatin Regulator Library

Pooled Library

#200011

Purpose

CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

Depositor

Bradley Bernstein, Gabriel Griffin, Robert Manguso

Article

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only
CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

Pooled Library

#223064

Purpose

Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

Depositor

Jonathan Schmid-Burgk

Article

Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 23, 2025

Availability

Academic Institutions and Nonprofits only
BW-Para

Bacterial Strain

#172602

Purpose

The BW-Para E. coli strain is used to screen the functions of chimeric AraC/XylS transcription activators using beta-galactosidase assays.

Depositor

Liskin Swint-Kruse

Article

Picard et al Proteins. 2021 Aug 8. doi: 10.1002/prot.

Bacterial Resistance

None

Available since

Dec. 22, 2022

Availability

Academic Institutions and Nonprofits only
Anti-Kv1.3 K+ channel [L23/27R] (Recombinant Antibody)

Antibody

#183000-rAb

Purpose

Anti-Kv1.3 K+ channel (Rat) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Recommended Applications

Immunohistochemistry and Western Blot

Reactivity

Human, Mouse, and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

June 13, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-HCN1 [N70/28R] (Recombinant Antibody)

Antibody

#180092-rAb

Purpose

Anti-HCN1 (Rat) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Immunohistochemistry and Western Blot

Reactivity

Human, Mouse, and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

March 30, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-CASPR/Neurexin IV [K65/35R] (Recombinant Antibody)

Antibody

#182999-rAb

Purpose

Anti-CASPR/Neurexin IV (Rat) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Recommended Applications

Immunohistochemistry and Western Blot

Reactivity

Human, Mouse, and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

May 31, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-Slo1/BKAlpha maxi-K+ channel [L6/60R] (Recombinant Antibody)

Antibody

#182998-rAb

Purpose

Anti-Slo1/BKAlpha maxi-K+ channel (Mouse) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Recommended Applications

Immunohistochemistry and Western Blot

Reactivity

Human, Mouse, Rat, and Zebrafish

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

May 31, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-Mitofusin-1 [N111/24R] (Recombinant Antibody)

Antibody

#184214-rAb

Purpose

Anti-Mitofusin-1 (Mouse) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Immunocytochemistry

Reactivity

Mouse and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

Aug. 22, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-Lgi1 [N283/7R] (Recombinant Antibody)

Antibody

#191815-rAb

Purpose

Anti-Lgi1 (Mouse) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Western Blot

Reactivity

Human, Mouse, and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

Jan. 30, 2023

Availability

Industry, Academic Institutions, and Nonprofits
Anti-GFAP [N206A/8R] (Recombinant Antibody)

Antibody

#193445-rAb

Purpose

Anti-GFAP (Human) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Immunohistochemistry and Western Blot

Reactivity

Human, Mouse, and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

Jan. 30, 2023

Availability

Industry, Academic Institutions, and Nonprofits
Anti-ASIC1 [N271/44R] (Recombinant Antibody)

Antibody

#184198-rAb

Purpose

Anti-ASIC1 (Mouse) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Western Blot

Reactivity

Mouse and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

Aug. 22, 2022

Availability

Industry, Academic Institutions, and Nonprofits
Anti-SUR1 [N289/16R] (Recombinant Antibody)

Antibody

#180113-rAb

Purpose

Anti-SUR1 (Rat) recombinant mouse monoclonal antibody

Depositor

James Trimmer

Article

Andrews et al Elife. 2019 Jan 22;8. pii: 43322. doi: 1

Recommended Applications

Immunocytochemistry

Reactivity

Mouse and Rat

Source Species

Mouse

Isotype

IgG2a

Trial Size

Available to purchase

Available since

March 30, 2022

Availability

Industry, Academic Institutions, and Nonprofits