We narrowed to 13,205 results for: lic

1. pCAGmCherry-gRNA

   Plasmid

   #87110

   Purpose

   gRNA cloning vector with CAGmCherry

   Depositor

   Juan Belmonte

   Article

   Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

   Type

   Empty backbone

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   March 30, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pBabe-TetCMV-puro-mCherry-PA-Rac1

   Plasmid

   #22035

   Purpose

   Expression of photoactivatable Rac1

   Depositor

   Klaus Hahn

   Article

   Wu et al Nature. 2009 Sep 3. 461(7260):104-8.

   Insert

   mCherry-PA-Rac1 (RAC1 Avena sativa (oat), Human)
   

   Use

   Retroviral

   Expression

   Mammalian

   Mutation

   Rac1 starts at I4 and contains mutations Q61L, E9…

   Promoter

   Tet-CMV

   Available Since

   Sept. 11, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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3. pET42b-HF-BE3

   Plasmid

   #87438

   Purpose

   Expresses HF-BE3-NLS with an N-terminal His Tag (His6) for bacterial expression

   Depositor

   David Liu

   Article

   Rees et al Nat Commun. 2017 Jun 6;8:15790. doi: 10.

   Insert

   HF-BE3 (Apobec1 Human, Bacillus phage PBS2, Rat)
   

   Tags

   His6

   Expression

   Bacterial

   Available Since

   June 13, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pNIC-ZB-SPRTNwt-FL

   Plasmid

   #110217

   Purpose

   Expression in E. coli of full-length wild-type SPRTN protein, with His and ZB tags at N-terminus.

   Depositor

   Kristijan Ramadan

   Article

   Vaz et al Mol Cell. 2016 Nov 17;64(4):704-719. doi

   Insert

   SPRTN (SPRTN Human)
   

   Expression

   Bacterial

   Mutation

   P296L (see depositor comments below)

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA3.1 Mfn2-HA S27A

   Plasmid

   #139193

   Purpose

   Expresses C-terminal HA tagged human Mfn2 S27A in mammalian cells

   Depositor

   Allan Weissman

   Article

   Leboucher et al Mol Cell. 2012 Aug 24;47(4):547-57. doi:

   Insert

   MFN2 (MFN2 Human)
   

   Tags

   3HA

   Expression

   Mammalian

   Mutation

   Serine 27 to Alanine

   Promoter

   CMV promoter

   Available Since

   March 23, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCR4_miniFXN_8

   Plasmid

   #234361

   Purpose

   Mini FXN plasmid with a partial deletion of the 5' UTR and a large deletion of intron 1 in FXN. Does not contain GAA repeats.

   Depositor

   Marek Napierala

   Article

   Li et al Hum Gene Ther. 2020 Aug;31(15-16):839-85

   Insert

   FXN (FXN Human)
   

   Use

   Cloning

   Tags

   Flag Tag

   Mutation

   There is a partial deletion in the 5'UTR of …

   Available Since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pcDNA3.1 Mfn2-HA S27D

   Plasmid

   #139194

   Purpose

   Expresses C-terminal HA tagged human Mfn2 S27D in mammalian cells

   Depositor

   Allan Weissman

   Article

   Leboucher et al Mol Cell. 2012 Aug 24;47(4):547-57. doi:

   Insert

   MFN2 (MFN2 Human)
   

   Tags

   2HA

   Expression

   Mammalian

   Mutation

   Serine 27 to Aspartic Acid

   Promoter

   CMV promoter

   Available Since

   Nov. 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pIRES2-EGFP-deltaNp53:WTp53

   Plasmid

   #49244

   Purpose

   expresses human p53 deltaN linked to full length p53 with C terminal His tag and also expresses EGFP in mammalian cells

   Depositor

   Dylan Taatjes

   Article

   Lin et al Aging Cell. 2013 Oct;12(5):863-72. doi:

   Insert

   p53 deltaN and p53 WT (TP53 Human)
   

   Tags

   His and IRES-EGFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Dec. 27, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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9. lentiCRISPR v2-sgBAP1-1

   Plasmid

   #125837

   Purpose

   KO BAP1 gene

   Depositor

   Boyi Gan

   Article

   Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

   Insert

   BAP1 (BRCA1 associated protein 1) (BAP1 Human)
   

   Use

   Lentiviral

   Available Since

   June 5, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pDONR223_TRAF5_WT

    Plasmid

    #82167

    Purpose

    Gateway Donor vector containing TRAF5 , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, William Hahn, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    TRAF5 (TRAF5 Human)
    

    Use

    Gateway entry vector

    Mutation

    WT

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHIV-INK4A-mOrange2

    Plasmid

    #110730

    Purpose

    Mammalian Expression of p16INK4A IRES H2B-mOrange2

    Depositor

    Robert Judson-Torres

    Article

    Zeng et al Cancer Cell. 2018 Jul 9;34(1):56-68.e9.

    Insert

    p16INK4A IRES H2B-mOrange2 (CDKN2A Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    July 25, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. PGK-HA-PGRN-LAMP1TM

    Plasmid

    #234873

    Purpose

    Lentiviral plasmid expressing HA-tagged human progranulin that is fused to the transmembrane domain and cytosolic tail of LAMP-1. Enables lysosomal delivery of progranulin without secretion.

    Depositor

    Andrew Arrant

    Article

    Davis et al J Biol Chem. 2021 Sep;297(3):100993. doi

    Insert

    Progranulin (GRN Human)
    

    Use

    Lentiviral

    Tags

    HA tag and LAMP-1 transmembrane domain and cytoso…

    Expression

    Mammalian

    Promoter

    PGK

    Available Since

    April 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. lentiCRISPR v2-sgBAP1-2

    Plasmid

    #125838

    Purpose

    KO BAP1 gene

    Depositor

    Boyi Gan

    Article

    Zhang et al Nat Cell Biol. 2018 Oct;20(10):1181-1192

    Insert

    BAP1 (BRCA1 associated protein 1) (BAP1 Human)
    

    Use

    Lentiviral

    Available Since

    June 5, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCas-MmdCas12m-CBE1

    Plasmid

    #192284

    Purpose

    MmdCas12m-CBE1 expressed under a constitutive promoter

    Depositor

    John van der Oost

    Article

    Wu et al Mol Cell. 2022 Dec 1;82(23):4487-4502.e7

    Insert

    MmdCas12m-CDA-UGI
    

    Use

    CRISPR

    Expression

    Bacterial

    Mutation

    D485A

    Promoter

    PJ23108

    Available Since

    Dec. 19, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCas9_sgRNA_0

    Plasmid

    #70763

    Purpose

    expresses Ustilago maydis codon-optimized Cas9, contains U. maydis U6 promoter, is self-replicating

    Depositor

    Regine Kahmann

    Article

    Schuster et al Fungal Genet Biol. 2015 Sep 11. pii: S10

    Inserts

    U6 promoter
    cas9
    tnos terminator
    

    Use

    Self-replicating in ustilago maydis, conferring c…

    Tags

    N-terminal NLS, C-terminal HA-tag +NLS

    Mutation

    Streptococcus pyogenes gene codon-optimized for U…

    Promoter

    U6 from Ustilago maydis and synthetic otef promot…

    Available Since

    Nov. 12, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCMV-HF-BE3

    Plasmid

    #87439

    Purpose

    Expresses HF-BE3 with C-terminal NLS in mammalian cells

    Depositor

    David Liu

    Article

    Rees et al Nat Commun. 2017 Jun 6;8:15790. doi: 10.

    Insert

    HF-BE3 (Apobec1 Human, Bacillus phage PBS2, Rat)
    

    Expression

    Mammalian

    Mutation

    Mammalian codon-optimized Cas9-HF

    Promoter

    CMV

    Available Since

    June 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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17. pL452-Sf3b1-K700E

    Plasmid

    #90425

    Purpose

    selectable HDR vector to introduce K700E mutation within mus Sf3b1 gene (for use with sgSf3b1(T1) and pL452(hygro)-Sf3b1-K700K plasmids enabling generation of hemizygous K700E mutation)

    Depositor

    Alex Minella

    Article

    Gupta et al Nucleic Acids Res. 2018 Nov 20. pii: 519

    Insert

    Sf3b1 - left and right homology arms (Sf3b1 Mouse)
    

    Use

    Homology-directed repair vector

    Available Since

    Nov. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. pcDNA6.2-YFP-CWT

    Plasmid

    #176689

    Purpose

    Fluorescent reporter for phagosomal escape of Staphylococcus aureus

    Depositor

    Martin Fraunholz

    Article

    Blattner et al PLoS Pathog. 2016 Sep 15;12(9):e1005857.

    Insert

    cell wall-targeting domain of Lysostaphin
    

    Tags

    YFP

    Expression

    Mammalian

    Mutation

    deletion of protase domain of Lysostaphin

    Promoter

    CMV

    Available Since

    Dec. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAS_4xMmaPylT_EF1_CRFR1-A95TAG-HA

    Plasmid

    #174900

    Purpose

    amber suppression mediated CRFR1 A95TAG expression in mammalian cells; transient or piggy bac mediated integration

    Depositor

    Simon Elsaesser

    Article

    Meineke et al Front Chem. 2021 Nov 11;9:768535. doi: 1

    Insert

    CRFR1 (Crhr1 Rat)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    A95TAG

    Promoter

    EF1

    Available Since

    Nov. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pDONR223_NMNAT3_WT

    Plasmid

    #81885

    Purpose

    Gateway Donor vector containing NMNAT3 , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, William Hahn, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    NMNAT3 (NMNAT3 Human)
    

    Use

    Gateway entry vector

    Mutation

    WT

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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