...Micropeptide killswitch for biomolecular condensates
AAV-CRISPRa-engineered fat cells fight cancer
Frugal ...interactions. Plus, the tools used here (also available as AAV Packaged on Request) will be useful for related studies.... https://doi.org/10.1038/s41586-025-09141-5
AAV-engineered adipocytes suppress tumor progression ...normally expressed in BAT. When donor-derived CRISPRa-AAV-treated WAT cells were transplanted into the vicinity...experiments. B) Constructs for tet-inducible CRISPRa-AAV engineering. Adapted from Nguyen et al. (2025) under...cell and gene therapy, so please check it out!
Find AAV-CRISPRa plasmids here!
Nguyen, H. P., et al. (2025...microenvironment (Nguyen et al., 2025).
The team used AAV9 to deliver CRISPRa components to adipose cells to...