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We narrowed to 638 results for: Nov

Showing: 161 - 180 of 638 results
  1. What the HEK?

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    Blog Post
    ...Netherlands. Transformation of HEK cells with adenovirus 5 DNA was postdoc Frank Graham’s 293rd experiment...transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. (2002...Organisms 10 Tips for Mammalian Cell Culture Adenoviral Vector Production and Troubleshooting Additional...
  2. Celebrating the 2024 Nobel Prize in Chemistry

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    Blog Post
    ...we’ve seen so far!). They started by designing a novel topology, then iteratively generated 3D models and...Although Top7 was designed simply to be stable and novel, the principles that created it have been applied...the Baker Lab and others. The introduction of de novo designed proteins also helped researchers understand...Stoddard, B. L., & Baker, D. (2003). Design of a Novel Globular Protein Fold with Atomic-Level Accuracy...
  3. Addgene Depositors Get More Citations

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    Blog Post
    ...She is particularly interested in exploring how innovative tools influence the direction of scientific research...    Neil Thompson is an Assistant Professor of Innovation and Strategy at the MIT Sloan School of Management...performance, and randomized control trials in innovation. Visit his website at: http://www.neil-t.com/...
  4. Celebrate National Book Month with Addgene

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    Blog Post
    ...is the first 3 books of a larger epic of fantasy novels. Set in a world where 1000 years ago the hero lost...     - Jason Snair, Product Designer Sarum: The Novel of England by Edward Rutherfurd "A 10,000 year history...undergraduate degree in English, I had lapsed. Baker’s novel reignited my appreciation of poetry, and I’ve been...
  5. A History of Genome Engineering in Popular Culture

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    Blog Post
    ...animal testing and modifications. The premise of the novel involves Dr. Moreau who creates human-animal hybrids... writer Jack Williamson who used it in his 1951 novel Dragon’s Island. In 1976, the world’s first genetic...against a genetically engineered superhuman Khan. The novel, Inferno (2013) and the movie version (2016) stars...editors which can help accelerate the engineering of novel base editor proteins. She is particularly interested...Leung E, Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ (2011) Targeted Genome Editing Across...
  6. Michael Koeris' Journey from Grad Student to Entrepreneur: The Story of Sample 6

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    Blog Post
    ... changed its name from Novophage to Sample 6. To learn more about Novophage's successful transformation...Koeris and Lu founded the biotech startup company, Novophage. As you'll hear Dr. Koeris explain however, the...firm, Flagship Ventures, Koeris helped change Novophage's focus. The company went from developing therapeutics...
  7. 15 Hot Plasmids from 2017

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    Blog Post
    ...includes four promoters, six fluorophores with nonoverlapping emission spectra (N- and C-terminal tags for...using these tools in virtually any vertebrate. This novel AAV approach allows you to target and functionally...Podcast Segment on This New AAV Tool    mCyRFP1: Novel fluorescent protein that enables imaging of two ...Lin and Ryohei Yasuda have teamed up to develop a novel monomeric cyan-excitable red fluorescent protein...
  8. Targeted Mutagenesis with EvolvR

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    Blog Post
    ...Berkeley, provides a new approach for generating novel genetic variants in bacteria. Read on to learn about...of EvolvR The Dueber Lab used EvolvR to discover novel genotypes that result in a spectinomycin resistant...spectinomycin, rpsE. These results not only uncovered novel resistance genotypes, but also provide a better ...
  9. AAV Q&A with Tim Miles

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    Blog Post
    ...user Resources on Addgene.org Find Adenovirus Plasmids Adenovirus Guide Page Subscribe to Viral Vectors...virus in your research - a primer for beginners Adenoviral delivery of CRISPR/Cas9 Tips for a first time...
  10. 3 Challenges in Plant Synthetic Biology

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    Blog Post
    ...; synthetic biology is required to achieve this novel and unique phenotype. It’s an unexpected use of ...creating new forums and opportunities for open innovation in plant synthetic biology. In our case, we selected...off patent, or not patented, and building our own novel pieces where applicable. We will also be working...
  11. Reflections and Looking Ahead

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    Blog Post
    ...our partnership with the Institute for Protein Innovation (IPI), we expanded a growing collection of thoroughly...enter 2025, your feedback continues to guide our innovation.  In response to a demand for more AAV viral ...extensive plasmid database — because we believe that innovation flourishes when data are shared. The scientific...look ahead, I am excited to continue to grow and innovate with your help and guidance. Every plasmid shared...
  12. Celebrating 15 Years of Scientific Sharing

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    Blog Post
    ...one, is a sterling example of collaboration and innovation between legal and scientific fields.” Thanks ... every day for their dedication, flexibility, innovative thinking, and openness to team work.   Company...positions. We have an awesome talent pipeline. Turnover at Addgene is about half of what is standard in...
  13. 5 Steps to Writing Grant Proposals for Grad Students

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    Blog Post
    ...Research Strategy highlights i) the significance and innovation of the project and ii) how you, the expert, will...writing a proposal to test hypotheses and develop novel technologies! If data from a publication or preliminary...funding. Convince the readers why and how your innovation will address a variety of challenges and impact...
  14. Hot Plasmids and Viral Preps - July 2021

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    Blog Post
    .... https://doi.org/10.1101/2020.05.04.076067    Novel fluorescent enzyme biosensors provide direct, specific...optimization. Claudia Vickers’s lab has designed novel SL fluorescent biosensors by integrating a SL-insensitive...parasitic Striga hermonthica SL receptor HTL7. This novel type of biosensors could be used in high throughput...As a result, agricultural applications of these novel biosensors could have a major economic impact.   ...
  15. A Look at Addgene's QC Process

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    Blog Post
    ...assembled into a circularized plasmid sequence de novo (without the use of a reference sequence) using ...the plasmid, QC scientists will first align the de novo NGS result to the deposited sequence(s) in SnapGene...if one was provided. If no reference is given, de novo assembly in Geneious can still provide additional...
  16. Viral Vectors 101: Virus Safety

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    Blog Post
    ... in the lab are gamma retrovirus, lentivirus, adenovirus, and adeno-associated virus (AAV). The least ...is usually classified as a BSL-1 safety level. Adenovirus is similar to AAV in that it does not integrate...integrate into the host’s genome. However, some adenovirus strains are known to cause respiratory diseases ...
  17. Meet the New Addgene Board Members!

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    Blog Post
    ...of the company.  Ultragenyx’s goal is to develop novel products for the treatment of rare and ultra-rare...was the Head of Oncology Target Discovery at the Novartis Institutes for Biomedical Research. Drug development...are less common, they can be very impactful. At Novartis, Stegmeier deposited the ClonTracer Barcoding ...built create inefficiencies that ultimately make innovation and science slow,” Vandenberghe says. “The continuous...
  18. Viral Vectors 101: Producing Your rAAV

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    Blog Post
    ...replicate itself and depends on helper viruses like adenovirus (Ad) or herpes simplex virus to facilitate efficient...a “helper-free” system, in which the required adenoviral helper genes are supplied on two different packaging..., J. (1999). Titration of AAV-2 particles via a novel capsid ELISA: Packaging of genomes can limit production...
  19. Plasmids 101: Multicistronic Vectors

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    Blog Post
    ...expressing your gene, especially if you are studying a novel gene, is not always a straightforward process. Rather... of interest, scientists have instead developed novel methods to co-express your gene along with a reporter...more time developing the clever experiments and innovative solutions necessary for advancing the field. ...
Showing: 161 - 180 of 638 results