We narrowed to 529 results for: arl

1. Viral Vectors 101: AAV Serotypes and Tissue Tropism

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   Blog Post

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   Jan. 16, 2025, 2:15 p.m.

   ...al., 2023; Wu, Asokan, et al., 2006). AAV6 is particularly well-suited for transduction of lung cells via...

2. Viral Vectors 101: Optogenetic Tools

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   Blog Post

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   June 27, 2023, 1:15 p.m.

   ...over when and where the receptor is activated.  Similarly, PTLs are special, covalently linked molecules...

3. Technologies Enabled by NanoLuc® Luciferase

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   Blog Post

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   Feb. 8, 2018, 12:17 p.m.

   ...orange fluorescent protein, CyOFP1. CyOFP1 was molecularly evolved from mNeptune2 through 33 mutations and...

4. Plasmids 101: Dimers and Multimers

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   Blog Post

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   Jan. 10, 2023, 2:15 p.m.

   ...plasmid multimerization. Plasmid Multimerization Early studies on plasmid topology recorded plasmid multimerization...

5. Antibodies 101: The Basics of Western Blotting

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   Blog Post

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   March 8, 2021, 2:41 p.m.

   ...could contain unintended cross-reactive proteins. Similarly, if you vary the experimental conditions from ...

6. Technique: Probe Phage Genomes for Host Binding Proteins

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   Blog Post

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   Sept. 29, 2016, 2:30 p.m.

   ... and a few proteases knocked out making them particularly useful for protein production), then dilute ...

7. Finding Your Perfect Job After University

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   Blog Post

   Published

   Jan. 12, 2016, 3:30 p.m.

   ... a type of pediatric kidney cancer. This was particularly interesting as I had just completed my thesis...

8. Building Global Connections with the International Mentorship Program USA-EUROPE

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   Blog Post

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   Nov. 6, 2015, 3:30 p.m.

   ...President from the non-profit IMFAHE, Inc. She is particularly interested in breast cancer and metastasis as...

9. A Practical Guide to Optimizing AAV DIO and FLEx Vector Expression

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   Blog Post

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   Nov. 2, 2021, 1:15 p.m.

   ... or excise a gene that is located between them. Early recombinase-dependent vector designs used a lox-...

10. An “elegans” Approach to Better CRISPR/Cas9 Editing Efficiency

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    Blog Post

    Published

    Dec. 17, 2020, 1:30 p.m.

    ...the “elegans” methods outlined in this post – particularly the use of co-selection methods – could greatly...

11. RNA Interference in Plant Biology: New Tools for an Old Favorite

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    Blog Post

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    Oct. 27, 2020, 1:15 p.m.

    ...silencing plants. Non-destructive methods, most popularly with a fluorescent reporter, directly couple silencing...

12. Important Considerations When Using AAVs

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    Blog Post

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    June 13, 2017, 2:30 p.m.

    ...receptors (i.e. chemogenetics vs. optogenetics) I’m particularly interested in using chemogenetic and optogenetic...

13. Lambda Red: A Homologous Recombination-based Technique for Genetic Engineering

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    Blog Post

    Published

    Dec. 15, 2016, 3:57 p.m.

    ...Medicine at the University of Washington. She is particularly interested in science communication and in vitro...

14. Deep Dive: Statistical Tests (Comparisons)

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    Blog Post

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    March 7, 2023, 2:15 p.m.

    ...Groups with Ordinal Dependent Variables: A Monte Carlo Simulation Study. Front. Appl. Math. Stat. Volume...

15. Sequencing Options for CRISPR Genotyping

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    Blog Post

    Published

    Oct. 4, 2016, 2:30 p.m.

    ...25566793. PubMed Central PMCID: PMC4349094. 3. Bell, Charles C., et al. "A high-throughput screening strategy...

16. Typing CRISPR Systems

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    Blog Post

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    March 18, 2025, 1:15 p.m.

    ...about 90% of identified CRISPR-Cas in bacteria and nearly 100% in archaea, though Class 1 remains largely...

17. Antibodies 101: Introduction to Antibodies

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    Blog Post

    Published

    Jan. 19, 2021, 2:15 p.m.

    ...   Enzyme-linked immunosorbent assay (ELISA) Similarly, ELISA is used to detect the presence of a single...

18. Illuminating Choices: A Guide to Selecting Fluorescent Dyes and Ligands

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    Blog Post

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    March 21, 2024, 1:15 p.m.

    ...stable signal over extended periods, which is particularly beneficial when studying dynamic processes like...

19. Fluorescent Proteins 101: Photoactivatable Fluorescent Proteins

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    Blog Post

    Published

    April 25, 2017, 2:30 p.m.

    ...leading to dimmer fluorescence. In fact, many of the early reversible PA-FPs also display this “negative” photoswitching...

20. Hassle-free 96-well Format Epitope Tagging Using Cas9 Ribonucleoprotein

    Type

    Blog Post

    Published

    June 28, 2018, 3:01 p.m.

    ...spectrometry to identify the interacting proteins. Similarly, in ChIP-seq assays, chromatin fragments that ...