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We narrowed to 67 results for: dcas9

Showing: 41 - 60 of 67 results

  1. CRISPR 101: Cytosine and Adenine Base Editors

    Type
    Blog Post
    Published
    Feb. 13, 2025, 2:15 p.m.
    ...coupling a cytidine deaminase with the inactive dCas9 (Komor et al., 2016). These fusions convert cytosine...an inhibitor of uracil DNA glycosylase (UGI) to dCas9 prevents base excision repair, which would change.... To do so, they used a Cas nickase, instead of dCas9. The resulting editor, BE3, nicks the unmodified...

  2. How to Design Your gRNA for CRISPR Genome Editing

    Type
    Blog Post
    Published
    Sept. 24, 2020, 1:15 p.m.
    ...inhibition) technologies – a nuclease-dead Cas9 (dCas9) is directed near the promoter of a target gene....position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression. Nucleic Acids...

  4. 10 Great Guest Posts We're Thankful For

    Type
    Blog Post
    Published
    Nov. 18, 2016, 3 p.m.
    ... system that uses modular RNA binding proteins, dCas9, and a modified gRNA to direct a variety of customizable...

  6. Targeted Mutagenesis with EvolvR

    Type
    Blog Post
    Published
    Feb. 21, 2019, 1:15 p.m.
    ...diversification by targeting a site of interest with dCas9 fused to the Activation Induced Cytidine Deaminase...

  20. Hot Plasmids Spring 2024

    Type
    Blog Post
    Published
    May 23, 2024, 1:15 p.m.
    ...of applications, including CRISPR activation by dCas9-VPR, prime editing, and delivery of disease-relevant...
Showing: 41 - 60 of 67 results