pcDNA3-FLAG-DDB1 Citations (12)

Originally described in: WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y Genes Dev. 2008 Apr 1. 22(7):866-71. PubMed Journal

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Articles Citing pcDNA3-FLAG-DDB1

Articles
Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. Wu Z, Chen Y, Yang T, Gao Q, Yuan M, Ma L. PLoS One. 2012;7(8):e43997. doi: 10.1371/journal.pone.0043997. Epub 2012 Aug 27. PubMed
The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels. Chen YA, Peng YJ, Hu MC, Huang JJ, Chien YC, Wu JT, Chen TY, Tang CY. Sci Rep. 2015 May 29;5:10667. doi: 10.1038/srep10667. PubMed
Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins. Shin YJ, Park SK, Jung YJ, Kim YN, Kim KS, Park OK, Kwon SH, Jeon SH, Trinh le A, Fraser SE, Kee Y, Hwang BJ. Sci Rep. 2015 Sep 16;5:14269. doi: 10.1038/srep14269. PubMed
HIV-host interactome revealed directly from infected cells. Luo Y, Jacobs EY, Greco TM, Mohammed KD, Tong T, Keegan S, Binley JM, Cristea IM, Fenyo D, Rout MP, Chait BT, Muesing MA. Nat Microbiol. 2016 Jul;1(7):16068. Epub 2016 May 23. PubMed
MNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1. Brown MC, Gromeier M. Cell Rep. 2017 Feb 7;18(6):1444-1457. doi: 10.1016/j.celrep.2017.01.023. PubMed
An efficient rapid system for assaying HBx-mediated transactivation. Zhou X, Shi H, Yang S, Sun P. Biotechnol Lett. 2017 Jul;39(7):1091-1099. doi: 10.1007/s10529-017-2334-1. Epub 2017 Apr 6. PubMed
A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-kappaB Inhibitory Activity of the HIV-2-Encoded Vpx. Landsberg CD, Megger DA, Hotter D, Ruckborn MU, Eilbrecht M, Rashidi-Alavijeh J, Howe S, Heinrichs S, Sauter D, Sitek B, Le-Trilling VTK, Trilling M. Front Immunol. 2018 Dec 19;9:2978. doi: 10.3389/fimmu.2018.02978. eCollection 2018. PubMed
Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation. Lu G, Yi J, Gubas A, Wang YT, Wu Y, Ren Y, Wu M, Shi Y, Ouyang C, Tan HWS, Wang T, Wang L, Yang ND, Deng S, Xia D, Chen RH, Tooze SA, Shen HM. Autophagy. 2019 Nov;15(11):1917-1934. doi: 10.1080/15548627.2019.1596484. Epub 2019 Mar 30. PubMed
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. Nowak M, Suenkel B, Porras P, Migotti R, Schmidt F, Kny M, Zhu X, Wanker EE, Dittmar G, Fielitz J, Sommer T. J Cell Sci. 2019 Sep 6;132(17). pii: jcs.233395. doi: 10.1242/jcs.233395. PubMed
CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. Fu SJ, Hu MC, Peng YJ, Fang HY, Hsiao CT, Chen TY, Jeng CJ, Tang CY. Cells. 2020 May 26;9(6). pii: cells9061332. doi: 10.3390/cells9061332. PubMed
Rational discovery of molecular glue degraders via scalable chemical profiling. Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Muller AC, Zuber J, Geyer M, Thoma NH, Kubicek S, Winter GE. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. PubMed
The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma. Houles T, Boucher J, Lavoie G, MacLeod G, Lin S, Angers S, Roux PP. Cell Death Discov. 2023 Dec 16;9(1):459. doi: 10.1038/s41420-023-01754-x. PubMed

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