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pcDNA3.1(+) Flag-His-ATM kd Citations (11)

Plasmid Article: Activation of the ATM kinase by ionizing radiation and phosphorylation of p53.
Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siliciano JD Science. 1998 Sep 11;281(5383):1677-9.
PubMed Journal

Articles Citing pcDNA3.1(+) Flag-His-ATM kd

Identification of lethal microRNAs specific for head and neck cancer. Lindenbergh-van der Plas M, Martens-de Kemp SR, de Maaker M, van Wieringen WN, Ylstra B, Agami R, Cerisoli F, Leemans CR, Braakhuis BJ, Brakenhoff RH. Clin Cancer Res. 2013 Oct 15;19(20):5647-57. doi: 10.1158/1078-0432.CCR-12-2295. Epub 2013 Aug 13. PubMed
The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase. Lai WL, Hung WY, Ching YP. Oncogene. 2014 Nov 6;33(45):5303-9. doi: 10.1038/onc.2013.481. Epub 2013 Nov 18. PubMed
Integrative radiation systems biology. Unger K. Radiat Oncol. 2014 Jan 11;9:21. doi: 10.1186/1748-717X-9-21. PubMed
Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage. Kubota S, Fukumoto Y, Ishibashi K, Soeda S, Kubota S, Yuki R, Nakayama Y, Aoyama K, Yamaguchi N, Yamaguchi N. J Biol Chem. 2014 Feb 28;289(9):5730-46. doi: 10.1074/jbc.M113.546655. Epub 2014 Jan 13. PubMed
Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala SK. Mol Cell Biol. 2016 Apr 15;36(9):1354-65. doi: 10.1128/MCB.01004-15. Print 2016 May 1. PubMed
miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Salzman DW, Nakamura K, Nallur S, Dookwah MT, Metheetrairut C, Slack FJ, Weidhaas JB. Nat Commun. 2016 Mar 21;7:10954. doi: 10.1038/ncomms10954. PubMed

Associated Plasmids

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. Chow HM, Cheng A, Song X, Swerdel MR, Hart RP, Herrup K. J Cell Biol. 2019 Mar 4;218(3):909-928. doi: 10.1083/jcb.201806197. Epub 2019 Jan 14. PubMed
Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Gross KM, Zhou W, Breindel JL, Ouyang J, Jin DX, Sokol ES, Gupta PB, Huber K, Zou L, Kuperwasser C. Cell Rep. 2019 Jul 9;28(2):394-407.e6. doi: 10.1016/j.celrep.2019.06.043. PubMed
Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V. Haematologica. 2020 Feb 6. pii: haematol.2019.234385. doi: 10.3324/haematol.2019.234385. PubMed
Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies. Sarkar A, Gandhi V. Mol Cell Biochem. 2021 Jan;476(1):417-423. doi: 10.1007/s11010-020-03917-1. Epub 2020 Sep 29. PubMed
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N. Nat Commun. 2021 Oct 27;12(1):6207. doi: 10.1038/s41467-021-26240-9. PubMed

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