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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA
Nat Biotechnol. 2015 May;33(5):510-7. doi: 10.1038/nbt.3199. Epub 2015 Apr 6.
PubMed Journal

Plasmids from Article

ID Plasmid  
61355pcDNA-dCas9-HA
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61356pcDNA-dCas9-FLp300
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61357pcDNA-dCas9-p300 Core
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61358pcDNA-dCas9-p300 Core (D1399Y)
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61359pcDNA-dCas9-p300 Core (1645/1646 RR/EE)
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61361pcDNA-dCas9-p300 Core (C1204R)
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61362pcDNA-dCas9-p300 Core (Y1467F)
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61363pcDNA-dCas9-p300 Core (1396/1397 SY/WW)
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61364pcDNA-dCas9-p300 Core (H1415A/E1423A/Y1424A/L1428S/Y1430A/H1434A)
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61365pcDNA3.3-Nm-dCas9-p300 Core
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61366pZDonor-Nm-Cas9-gRNA-hU6
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