Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnacion-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC
Cancer Discov. 2020 Apr 27. pii: 2159-8290.CD-19-0959. doi: 10.1158/2159-8290.CD-19-0959. PubMed Article
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnacion-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC
Cancer Discov. 2020 Apr 27. pii: 2159-8290.CD-19-0959. doi: 10.1158/2159-8290.CD-19-0959. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 156180 | pLentiCMVblast_SLC38A2_wt | CMV-driven expression of sgRNA-resistant SLC38A2 wild-type cDNA. |
| 156181 | pLentiCMVblast_SLC38A2_N82A | CMV-driven expression of sgRNA-resistant SLC38A2 N82A mutant cDNA. |
| 156182 | pInducer20_SLC38A2_wt | Dox-inducible expression of sgRNA-resistant SLC38A2 wild-type cDNA. |
| 156183 | pInducer20_SLC38A2_N82A | Dox-inducible expression of sgRNA-resistant SLC38A2 N82A mutant cDNA. |