Skip to main content
Holiday Schedule: Addgene will be closed November 26th & 27th for the Thanksgiving Holiday. Order processing and shipping may be delayed during this week. For questions about your shipment please contact [email protected].
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

A simplified cell-based assay to identify coronavirus 3CL protease inhibitors.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A
bioRxiv. 2020 Aug 29. doi: 10.1101/2020.08.29.272864.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
160278pLEX307-SARS-CoV-2-3CLAllows for constituitive mammalian expression of the SARS-CoV-2 3CL protease via transfection or lentivirus
Loading...
160279pLEX307-SARS-CoV-2-3CL-C145AAllows for constituitive mammalian expression of the SARS-CoV-2 3CL protease with C145A mutation via transfection or lentivirus
Loading...
160280pLEX307-SARS-CoV-3CLAllows for constituitive mammalian expression of the SARS-CoV 3CL protease via transfection or lentivirus
Loading...
160281pLEX307-SARS-CoV-3CL-C145AAllows for constituitive mammalian expression of the SARS-CoV 3CL protease with C145A mutation via transfection or lentivirus
Loading...
160282pLEX307-MERS-CoV-3CLAllows for constituitive mammalian expression of the MERS-CoV 3CL protease via transfection or lentivirus
Loading...
160283pLEX307-MERS-CoV-3CL-C148AAllows for constituitive mammalian expression of the MERS-CoV 3CL protease with C145A mutation via transfection or lentivirus
Loading...
160284pLEX307-Bat-CoV-HKU9-3CLAllows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease via transfection or lentivirus
Loading...
160285pLEX307-Bat-CoV-HKU9-3CL-C144AAllows for constituitive mammalian expression of the Bat-CoV-HKU9 3CL protease with C145A mutation via transfection or lentivirus
Loading...
160286pLEX307-HCoV-NL63-3CLAllows for constituitive mammalian expression of the HCoV-NL63 3CL protease via transfection or lentivirus
Loading...
160288pLEX307-IBV-3CLAllows for constituitive mammalian expression of the IBV 3CL protease via transfection or lentivirus
Loading...
160289pLEX307-IBV-3CL-C143AAllows for constituitive mammalian expression of the IBV 3CL protease with C143A mutation via transfection or lentivirus
Loading...