Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Tuck BJ, Miller LVC, Katsinelos T, Smith AE, Wilson EL, Keeling S, Cheng S, Vaysburd MJ, Knox C, Tredgett L, Metzakopian E, James LC, McEwan WA
Cell Rep. 2022 May 3;39(5):110776. doi: 10.1016/j.celrep.2022.110776. PubMed Article
Tuck BJ, Miller LVC, Katsinelos T, Smith AE, Wilson EL, Keeling S, Cheng S, Vaysburd MJ, Knox C, Tredgett L, Metzakopian E, James LC, McEwan WA
Cell Rep. 2022 May 3;39(5):110776. doi: 10.1016/j.celrep.2022.110776. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 187834 | pAAV-hSyn-eGFP-P2A-LgBiT-NLS | Expression of eGFP-P2A-LgBiT-NLS from human synapsin promoter via adeno-associated virus for neuronal expression. |
| 187835 | pRK172-6xHis-0N4R-P301S-tau-HiBiT | Expression of 6xHis-tagged P301S tau of 0N4R isoform with a C-terminal HiBiT tag for bimolecular luminescence with LgBiT. |