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miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3zeta.
Jung HM, Phillips BL, Chan EK
Mol Cancer. 2014 Apr 8;13(1):80. doi: 10.1186/1476-4598-13-80.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
53694pMiR-E6AP-3'UTRLuciferase reporter assay for microRNA binding on E6AP 3'UTR
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53695pMiR-E6AP-3'UTR-miR-375-mutLuciferase reporter assay for E6AP 3'UTR with point mutation on miR-375 binding site
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53696pMiR-HPV16-E7Luciferase reporter assay for microRNA binding on HPV16 E7
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53697pMiR-HPV16-E7-m1Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
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53698pMiR-HPV16-E7-m2Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
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53699pMiR-HPV16-E1(partial)Luciferase reporter assay for microRNA binding on HPV16 E1
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53700pMiR-HPV16-E1-m3Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
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53701pMiR-HPV16-E1-m4Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
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53702pMiR-HPV16-E1-m5Luciferase reporter assay for HPV16 E7 with point mutation on miR-375 binding site
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53703pMiR-HPV16-E7/E1Luciferase reporter assay for microRNA binding on HPV16 E7/E1
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53704pMiR-HPV16-E7/E1-miR-375-m1-5Luciferase reporter assay for HPV16 E7/E1 with point mutation on miR-375 binding site
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