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Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
Jung HM, Patel RS, Phillips BL, Wang H, Cohen DM, Reinhold WC, Chang LJ, Yang LJ, Chan EK
Mol Biol Cell. 2013 Jun;24(11):1638-48, S1-7. doi: 10.1091/mbc.E12-12-0891. Epub 2013 Apr 3.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
53705pMiR-CIP2A(partial)Luciferase reporter assay for microRNA binding on CIP2A coding sequence
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53706pMiR-CIP2A-miR-375-mutALuciferase reporter assay for CIP2A with point mutation on miR-375 binding site
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53707pMiR-CIP2A-miR-375-mutBLuciferase reporter assay for CIP2A with point mutation on miR-375 binding site
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53708pMiR-CIP2A-miR-375-mutCLuciferase reporter assay for CIP2A with point mutation on miR-375 binding site
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53709pMiR-CIP2A-miR-375-mutDLuciferase reporter assay for CIP2A with point mutation on miR-375 binding site
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53710pMiR-CIP2A-miR-375-mutELuciferase reporter assay for CIP2A with point mutation on miR-375 binding site
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53711pMiR-CIP2A-miR-375-mutA&BLuciferase reporter assay for CIP2A with point mutation on miR-375 binding sites
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53712pMiR-CIP2A-miR-375-mutC&DLuciferase reporter assay for CIP2A with point mutation on miR-375 binding sites
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53713pMiR-CIP2A-stop-mutLuciferase reporter assay for CIP2A with mutated firefly stop codon
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53714pMiR-CIP2A-stop-mut-miR-375-mutA-ELuciferase reporter assay for CIP2A with mutated firefly stop codon that also has five miR-375 binding site mutations
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53754pMiR-CIP2A-miR-375-mutA-ELuciferase reporter assay for CIP2A with point mutation on miR-375 binding sites
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