963 results

1. pAAV-CaMKIIa-hChR2(H134R)-mCherry (AAV5)

   Viral Prep

   #26975-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-CaMKIIa-hChR2(H134R)-mCherry (#26975). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   CaMKII

   Tags

   mCherry

   Available since

   Feb. 15, 2018

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-CaMKIIa-mScarlet (AAV8)

   Viral Prep

   #131000-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-mScarlet (#131000). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-mScarlet plasmid DNA. CamKIIa-driven expression of mScarlet. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Marshel et al Science. 2019 Aug 9;365(6453). pii: scie

   Promoter

   CaMKII

   Tags

   mScarlet

   Available since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-CAG-FLEX-rc [Jaws-KGC-tdTomato-ER2] (AAV8)

   Viral Prep

   #84446-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-CAG-FLEX-rc [Jaws-KGC-tdTomato-ER2] (#84446). In addition to the viral particles, you will also receive purified pAAV-CAG-FLEX-rc [Jaws-KGC-tdTomato-ER2] plasmid DNA. CAG-driven, Cre-dependent expression of Jaws-KGC-tdTomato-ER2 for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Article

   Chuong et al Nat Neurosci. 2014 Aug;17(8):1123-9. doi

   Promoter

   CAG

   Tags

   None

   Available since

   June 21, 2024

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-mDlx-NLS-mRuby2 (AAV Retrograde)

   Viral Prep

   #99130-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Viviana Gradinaru

   Article

   Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

   Promoter

   mDLX5/6

   Tags

   mRuby2

   Available since

   Sept. 18, 2019

   Availability

   Academic Institutions and Nonprofits only

5. AAV-EF1a-jGCaMP8s-WPRE (AAV1)

   Viral Prep

   #176758-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from AAV-EF1a-jGCaMP8s-WPRE (#176758). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8s-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8s (more sensitive). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   EF1a

   Tags

   None

   Available since

   July 12, 2023

   Availability

   Academic Institutions and Nonprofits only

6. pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 (AAV Retrograde)

   Viral Prep

   #105540-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 (#105540). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.HI.eGFP-Cre.WPRE.SV40 plasmid DNA. Expression of EGFP-Cre from hSyn promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   Syn

   Tags

   EGFP

   Available since

   Sept. 27, 2018

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV8)

   Viral Prep

   #44362-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. Syn-driven, Cre-dependent, hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Article

   Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available since

   Sept. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-CaMKIIa-hM3D(Gq)-mCherry (AAV5)

   Viral Prep

   #50476-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-CaMKIIa-hM3D(Gq)-mCherry (#50476). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM3D(Gq)-mCherry plasmid DNA. CaMKIIa-driven hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Tags

   mCherry

   Available since

   Nov. 21, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-hSyn-DIO-mCherry (AAV5)

   Viral Prep

   #50459-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-hSyn-DIO-mCherry (#50459). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-mCherry plasmid DNA. hSyn-driven, Cre-dependent mCherry-expression control. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available since

   Jan. 27, 2017

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-hSyn-eNpHR 3.0-EYFP (AAV5)

    Viral Prep

    #26972-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSyn-eNpHR 3.0-EYFP (#26972). In addition to the viral particles, you will also receive purified pAAV-hSyn-eNpHR 3.0-EYFP plasmid DNA. hSyn-driven eNpHR 3.0-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    EYFP

    Available since

    Feb. 14, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-hSyn-hM4D(Gi)-mCherry (AAV8)

    Viral Prep

    #50475-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-hSyn-hM4D(Gi)-mCherry (#50475). In addition to the viral particles, you will also receive purified pAAV-hSyn-hM4D(Gi)-mCherry plasmid DNA. hSyn-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    Syn

    Tags

    mCherry

    Available since

    Oct. 3, 2016

    Availability

    Academic Institutions and Nonprofits only

12. pAAV hSyn FLEx mGFP-2A-Synaptophysin-mRuby (AAV1)

    Viral Prep

    #71760-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV hSyn FLEx mGFP-2A-Synaptophysin-mRuby (#71760). In addition to the viral particles, you will also receive purified pAAV hSyn FLEx mGFP-2A-Synaptophysin-mRuby plasmid DNA. Syn-driven, Cre-dependent expression of membrane-bound GFP and the presynaptic protein synaptophysin fused to mRuby. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Liqun Luo

    Article

    Beier et al Cell. 2015 Jul 30;162(3):622-34. doi: 10

    Promoter

    Tags

    mGFP, mRuby (Cre-dependent)

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

13. pAAV.CAG.GCaMP6f.WPRE.SV40 (AAV9)

    Viral Prep

    #100836-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.CAG.GCaMP6f.WPRE.SV40 (#100836). In addition to the viral particles, you will also receive purified pAAV.CAG.GCaMP6f.WPRE.SV40 plasmid DNA. CAG-driven GCaMP6f calcium sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

    Promoter

    CAG

    Tags

    None

    Available since

    March 19, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-EF1a-Flpo (AAV Retrograde)

    Viral Prep

    #55637-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-EF1a-Flpo (#55637). In addition to the viral particles, you will also receive purified pAAV-EF1a-Flpo plasmid DNA. EF1a-driven Flpo recombinase expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    None

    Available since

    April 2, 2019

    Availability

    Academic Institutions and Nonprofits only

15. pAAV_BiSSTe4_ChR2_mCherry (AAV PHP.eB)

    Viral Prep

    #213945-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiSSTe4_ChR2_mCherry (#213945). In addition to the viral particles, you will also receive purified pAAV_BiSSTe4_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the SST interneuron-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    mCherry

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-hSyn-DIO-hM3D(Gq)-mCherry (AAV Retrograde)

    Viral Prep

    #44361-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-DIO-hM3D(Gq)-mCherry (#44361). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM3D(Gq)-mCherry plasmid DNA. Syn-driven, Cre-dependent, hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

    Promoter

    Syn

    Tags

    mCherry (Cre-dependent)

    Available since

    Oct. 11, 2017

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV1)

    Viral Prep

    #44362-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. hSyn-driven, Cre-dependent, hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

    Promoter

    Syn

    Tags

    mCherry (Cre-dependent)

    Available since

    May 26, 2020

    Availability

    Academic Institutions and Nonprofits only

18. pGP-AAV-syn-jGCaMP7b-WPRE (AAV1)

    Viral Prep

    #104489-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-jGCaMP7b-WPRE (#104489). In addition to the viral particles, you will also receive purified pGP-AAV-syn-jGCaMP7b-WPRE plasmid DNA. Syn-driven jGCaMP7b calcium sensor. jGCaMP7b exhibits the brightest resting fluorescence of the jGCaMP7 variants, and can be used for imaging of small neuronal processes. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    June 7, 2018

    Availability

    Academic Institutions and Nonprofits only

19. pAAV_BiSSTe10_dTomato_nlsdTomato (AAV PHP.eB)

    Viral Prep

    #213814-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiSSTe10_dTomato_nlsdTomato (#213814). In addition to the viral particles, you will also receive purified pAAV_BiSSTe10_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the SST interneuron-targeting enhancer E10. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    dTomato

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-GFAP-hM4D(Gi)-mCherry (AAV5)

    Viral Prep

    #50479-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-GFAP-hM4D(Gi)-mCherry (#50479). In addition to the viral particles, you will also receive purified pAAV-GFAP-hM4D(Gi)-mCherry plasmid DNA. GFAP-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal silencing. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    GFAP

    Tags

    mCherry

    Available since

    June 8, 2018

    Availability

    Academic Institutions and Nonprofits only