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p3TP-lux Citations (22)

Originally described in: TGF beta signals through a heteromeric protein kinase receptor complex.
Wrana JL, Attisano L, Carcamo J, Zentella A, Doody J, Laiho M, Wang XF, Massague J Cell. 1992 Dec 11. 71(6):1003-14.
PubMed Journal

Articles Citing p3TP-lux

Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells. Ramirez AM, Wongtrakool C, Welch T, Steinmeyer A, Zugel U, Roman J. J Steroid Biochem Mol Biol. 2010 Feb 15;118(3):142-50. doi: 10.1016/j.jsbmb.2009.11.004. Epub 2009 Nov 17. PubMed
Epithelial to mesenchymal transition is impaired in colon cancer cells with microsatellite instability. Pino MS, Kikuchi H, Zeng M, Herraiz MT, Sperduti I, Berger D, Park DY, Iafrate AJ, Zukerberg LR, Chung DC. Gastroenterology. 2010 Apr;138(4):1406-17. doi: 10.1053/j.gastro.2009.12.010. Epub 2009 Dec 21. PubMed
TGF-beta inhibits muscle differentiation by blocking autocrine signaling pathways initiated by IGF-II. Gardner S, Alzhanov D, Knollman P, Kuninger D, Rotwein P. Mol Endocrinol. 2011 Jan;25(1):128-37. doi: 10.1210/me.2010-0292. Epub 2010 Nov 24. PubMed
A novel gain-of-function mutation of TGF-beta receptor II promotes cancer progression via delayed receptor internalization in oral squamous cell carcinoma. Park I, Son HK, Che ZM, Kim J. Cancer Lett. 2012 Feb 28;315(2):161-9. doi: 10.1016/j.canlet.2011.09.036. Epub 2011 Oct 8. PubMed
Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition. Leight JL, Wozniak MA, Chen S, Lynch ML, Chen CS. Mol Biol Cell. 2012 Mar;23(5):781-91. doi: 10.1091/mbc.E11-06-0537. Epub 2012 Jan 11. PubMed
Synergistic and multidimensional regulation of plasminogen activator inhibitor type 1 expression by transforming growth factor type beta and epidermal growth factor. Song X, Thalacker FW, Nilsen-Hamilton M. J Biol Chem. 2012 Apr 6;287(15):12520-8. doi: 10.1074/jbc.M111.338079. Epub 2012 Feb 10. PubMed
HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome. Wardwell-Ozgo J, Dogruluk T, Gifford A, Zhang Y, Heffernan TP, van Doorn R, Creighton CJ, Chin L, Scott KL. Oncogene. 2014 Feb 20;33(8):1017-26. doi: 10.1038/onc.2013.30. Epub 2013 Feb 25. PubMed
AAV-mediated administration of myostatin pro-peptide mutant in adult Ldlr null mice reduces diet-induced hepatosteatosis and arteriosclerosis. Guo W, Wong S, Bhasin S. PLoS One. 2013 Aug 1;8(8):e71017. doi: 10.1371/journal.pone.0071017. Print 2013. PubMed
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2. Lee YS, Lee SJ. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):E3713-22. doi: 10.1073/pnas.1309907110. Epub 2013 Sep 9. PubMed
The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding. Ferguson BW, Gao X, Zelazowski MJ, Lee J, Jeter CR, Abba MC, Aldaz CM. BMC Cancer. 2013 Dec 11;13:593. doi: 10.1186/1471-2407-13-593. PubMed
Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation. Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M. J Clin Invest. 2014 Jan;124(1):338-52. doi: 10.1172/JCI71526. Epub 2013 Dec 16. PubMed
Hepatitis B virus regulates apoptosis and tumorigenesis through the microRNA-15a-Smad7-transforming growth factor beta pathway. Liu N, Jiao T, Huang Y, Liu W, Li Z, Ye X. J Virol. 2015 Mar;89(5):2739-49. doi: 10.1128/JVI.02784-14. Epub 2014 Dec 24. PubMed
Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia. Niihori T, Ouchi-Uchiyama M, Sasahara Y, Kaneko T, Hashii Y, Irie M, Sato A, Saito-Nanjo Y, Funayama R, Nagashima T, Inoue S, Nakayama K, Ozono K, Kure S, Matsubara Y, Imaizumi M, Aoki Y. Am J Hum Genet. 2015 Dec 3;97(6):848-54. doi: 10.1016/j.ajhg.2015.10.010. Epub 2015 Nov 12. PubMed
Follistatin N terminus differentially regulates muscle size and fat in vivo. Zheng H, Qiao C, Tang R, Li J, Bulaklak K, Huang Z, Zhao C, Dai Y, Li J, Xiao X. Exp Mol Med. 2017 Sep 15;49(9):e377. doi: 10.1038/emm.2017.135. PubMed
Frizzled-8 integrates Wnt-11 and transforming growth factor-beta signaling in prostate cancer. Murillo-Garzon V, Gorrono-Etxebarria I, Akerfelt M, Puustinen MC, Sistonen L, Nees M, Carton J, Waxman J, Kypta RM. Nat Commun. 2018 May 1;9(1):1747. doi: 10.1038/s41467-018-04042-w. PubMed
Protein kinase CK2 activation is required for transforming growth factor beta-induced epithelial-mesenchymal transition. Kim S, Ham S, Yang K, Kim K. Mol Oncol. 2018 Oct;12(10):1811-1826. doi: 10.1002/1878-0261.12378. Epub 2018 Sep 21. PubMed
Transforming growth factor-beta downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling. Du L, Roberts JD Jr. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L20-L34. doi: 10.1152/ajplung.00319.2018. Epub 2018 Sep 27. PubMed
Identification of a Pathogenic TGFBR2 Variant in a Patient With Loeys-Dietz Syndrome. Luo X, Deng S, Jiang Y, Wang X, Al-Raimi AMA, Wu L, Liu X, Song Y, Chen X, Zhu F. Front Genet. 2020 May 27;11:479. doi: 10.3389/fgene.2020.00479. eCollection 2020. PubMed
A novel TGF-beta receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling. Son HK, Kim D, Lim Y, Kim J, Park I. BMC Cancer. 2020 Nov 27;20(1):1163. doi: 10.1186/s12885-020-07669-5. PubMed
Systematic Analysis of Cytostatic TGF-Beta Response in Mesenchymal-Like Hepatocellular Carcinoma Cell Lines. Gungor MZ, Uysal M, Ozturk M, Senturk S. J Gastrointest Cancer. 2021 Dec;52(4):1320-1335. doi: 10.1007/s12029-021-00704-z. Epub 2021 Aug 31. PubMed
PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs. Roudaut M, Idriss S, Caillaud A, Girardeau A, Rimbert A, Champon B, David A, Leveque A, Arnaud L, Pichelin M, Prieur X, Prat A, Seidah NG, Zibara K, Le May C, Cariou B, Si-Tayeb K. Stem Cell Reports. 2021 Dec 14;16(12):2958-2972. doi: 10.1016/j.stemcr.2021.10.004. Epub 2021 Nov 4. PubMed
A micellized bone morphogenetic protein-7 prodrug ameliorates liver fibrosis by suppressing transforming growth factor-beta signaling. Cho K, Kim NH, Seo SH, Song SH, Jeong CH, Kim HS, Um JE, Ku M, Yang J, Park JY, Ahn SH, Yook JI, Kim SU. Am J Cancer Res. 2022 Feb 15;12(2):763-778. eCollection 2022. PubMed

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