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pcDNA3.1 myc TSC1 Citations (9)

Originally described in: Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.
Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, Shen J, Guo R, Johnson CL, Kiguchi K, Walker CL J Cell Biol. 2006 Apr 24. 173(2):279-89.
PubMed Journal

Articles Citing pcDNA3.1 myc TSC1

Articles
Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes. Miyazaki M, McCarthy JJ, Esser KA. FEBS J. 2010 May;277(9):2180-91. doi: 10.1111/j.1742-4658.2010.07635.x. PubMed
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. Lim JS, Gopalappa R, Kim SH, Ramakrishna S, Lee M, Kim WI, Kim J, Park SM, Lee J, Oh JH, Kim HD, Park CH, Lee JS, Kim S, Kim DS, Han JM, Kang HC, Kim HH, Lee JH. Am J Hum Genet. 2017 Mar 2;100(3):454-472. doi: 10.1016/j.ajhg.2017.01.030. Epub 2017 Feb 16. PubMed
CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia. Chiang YJ, Liao WT, Ho KC, Wang SH, Chen YG, Ho CL, Huang SF, Shih LY, Yang-Yen HF, Yen JJ. Oncogene. 2019 Feb;38(9):1432-1447. doi: 10.1038/s41388-018-0507-6. Epub 2018 Sep 28. PubMed
miR-92b-3p-TSC1 axis is critical for mTOR signaling-mediated vascular smooth muscle cell proliferation induced by hypoxia. Lee J, Heo J, Kang H. Cell Death Differ. 2018 Dec 5. pii: 10.1038/s41418-018-0243-z. doi: 10.1038/s41418-018-0243-z. PubMed
The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex. Wu R, Dang F, Li P, Wang P, Xu Q, Liu Z, Li Y, Wu Y, Chen Y, Liu Y. Cell Metab. 2019 Mar 5;29(3):653-667.e6. doi: 10.1016/j.cmet.2018.11.006. Epub 2018 Dec 6. PubMed
The ERK1/2-ATG13-FIP200 signaling cascade is required for autophagy induction to protect renal cells from hypoglycemia-induced cell death. Guo W, Wang Q, Pan S, Li J, Wang Y, Shu Y, Chen J, Wang Q, Zhang S, Zhang X, Yue J. J Cell Physiol. 2021 Oct;236(10):6932-6947. doi: 10.1002/jcp.30354. Epub 2021 Mar 8. PubMed
Development of a versatile HPLC-based method to evaluate the activation status of small GTPases. Araki M, Yoshimoto K, Ohta M, Katada T, Kontani K. J Biol Chem. 2021 Nov 18:101428. doi: 10.1016/j.jbc.2021.101428. PubMed

Associated Plasmids

Exosomal miR-673-5p from fibroblasts promotes Schwann cell-mediated peripheral neuron myelination by targeting the TSC2/mTORC1/SREBP2 axis. Zhao Y, Liang Y, Xu Z, Liu J, Liu X, Ma J, Sun C, Yang Y. J Biol Chem. 2022 Mar;298(3):101718. doi: 10.1016/j.jbc.2022.101718. Epub 2022 Feb 11. PubMed
Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells. Teran OY, Zanotelli MR, Lin MJ, Cerione RA, Wilson KF. bioRxiv. 2023 Jan 3:2023.01.03.522657. doi: 10.1101/2023.01.03.522657. Preprint. PubMed

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