Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pLenti6-DEST PINK1-V5 WT Citations (9)

Originally described in: Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.
Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR Proc Natl Acad Sci U S A. 2005 Apr 19. 102(16):5703-8.
PubMed Journal

Articles Citing pLenti6-DEST PINK1-V5 WT

Articles
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. Glauser L, Sonnay S, Stafa K, Moore DJ. J Neurochem. 2011 Aug;118(4):636-45. doi: 10.1111/j.1471-4159.2011.07318.x. Epub 2011 Jun 6. PubMed
PINK1 and its familial Parkinson's disease-associated mutation regulate brain vascular endothelial inflammation. Yunfu W, Guangjian L, Ping Z, Yanpeng S, Xiaoxia F, Wei H, Jiang Y, Jingquan H, Songlin W, Hongyan Z, Yong L, Shi C. J Mol Neurosci. 2014 May;53(1):109-16. doi: 10.1007/s12031-013-0207-1. Epub 2014 Jan 3. PubMed
Optogenetic Control of Synaptic Composition and Function. Sinnen BL, Bowen AB, Forte JS, Hiester BG, Crosby KC, Gibson ES, Dell'Acqua ML, Kennedy MJ. Neuron. 2017 Feb 8;93(3):646-660.e5. doi: 10.1016/j.neuron.2016.12.037. Epub 2017 Jan 26. PubMed

Associated Plasmids

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Bartolome A, Garcia-Aguilar A, Asahara SI, Kido Y, Guillen C, Pajvani UB, Benito M. Mol Cell Biol. 2017 Sep 11. pii: MCB.00441-17. doi: 10.1128/MCB.00441-17. PubMed
Miro proteins prime mitochondria for Parkin translocation and mitophagy. Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A. EMBO J. 2019 Jan 15;38(2). pii: embj.201899384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30. PubMed
TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Yang RM, Tao J, Zhan M, Yuan H, Wang HH, Chen SJ, Chen Z, de The H, Zhou J, Guo Y, Zhu J. Cell Death Differ. 2019 Nov;26(11):2430-2446. doi: 10.1038/s41418-019-0311-z. Epub 2019 Mar 1. PubMed
Mitophagy protein PINK1 suppresses colon tumor growth by metabolic reprogramming via p53 activation and reducing acetyl-CoA production. Yin K, Lee J, Liu Z, Kim H, Martin DR, Wu D, Liu M, Xue X. Cell Death Differ. 2021 Aug;28(8):2421-2435. doi: 10.1038/s41418-021-00760-9. Epub 2021 Mar 15. PubMed
Labeling and measuring stressed mitochondria using a PINK1-based ratiometric fluorescent sensor. Uesugi R, Ishii S, Matsuura A, Itakura E. J Biol Chem. 2021 Nov;297(5):101279. doi: 10.1016/j.jbc.2021.101279. Epub 2021 Oct 5. PubMed
DELE1 tracks perturbed protein import and processing in human mitochondria. Fessler E, Krumwiede L, Jae LT. Nat Commun. 2022 Apr 6;13(1):1853. doi: 10.1038/s41467-022-29479-y. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.