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pRDA_118 Citations (4)

Originally described in: Genetic screens in isogenic mammalian cell lines without single cell cloning.
DeWeirdt PC, Sangree AK, Hanna RE, Sanson KR, Hegde M, Strand C, Persky NS, Doench JG Nat Commun. 2020 Feb 6;11(1):752. doi: 10.1038/s41467-020-14620-6.
PubMed Journal

Articles Citing pRDA_118

In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma. Dubrot J, Lane-Reticker SK, Kessler EA, Ayer A, Mishra G, Wolfe CH, Zimmer MD, Du PP, Mahapatra A, Ockerman KM, Davis TGR, Kohnle IC, Pope HW, Allen PM, Olander KE, Iracheta-Vellve A, Doench JG, Haining WN, Yates KB, Manguso RT. Immunity. 2021 Jan 20. pii: S1074-7613(21)00001-7. doi: 10.1016/j.immuni.2021.01.001. PubMed

Associated Plasmids

Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2. Sangree AK, Griffith AL, Szegletes ZM, Roy P, DeWeirdt PC, Hegde M, McGee AV, Hanna RE, Doench JG. Nat Commun. 2022 Mar 14;13(1):1318. doi: 10.1038/s41467-022-28884-7. PubMed

Associated Plasmids

Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs. Rebendenne A, Roy P, Bonaventure B, Chaves Valadao AL, Desmarets L, Arnaud-Arnould M, Rouille Y, Tauziet M, Giovannini D, Touhami J, Lee Y, DeWeirdt P, Hegde M, Urbach S, Koulali KE, de Gracia FG, McKellar J, Dubuisson J, Wencker M, Belouzard S, Moncorge O, Doench JG, Goujon C. Nat Genet. 2022 Aug;54(8):1090-1102. doi: 10.1038/s41588-022-01110-2. Epub 2022 Jul 25. PubMed
Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening. DeWeirdt PC, McGee AV, Zheng F, Nwolah I, Hegde M, Doench JG. Nat Commun. 2022 Sep 6;13(1):5255. doi: 10.1038/s41467-022-33024-2. PubMed

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