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pLX304_zeo_mmFbxw7_R505C Citations (1)

Originally described in: Inactivation of Fbxw7 impairs dsRNA sensing and confers resistance to PD-1 blockade.
Gstalder C, Liu D, Miao D, Lutterbach B, DeVine AL, Lin C, Shettigar M, Pancholi P, Buchbinder EI, Carter SL, Manos MP, Rojas-Rudilla V, Brennick R, Gjini E, Chen PH, Lako A, Rodig S, Yoon CH, Freeman GJ, Barbie DA, Hodi FS, Miles W, Van Allen EM, Haq R Cancer Discov. 2020 May 5. pii: 2159-8290.CD-19-1416. doi: 10.1158/2159-8290.CD-19-1416. PubMed Journal

Articles Citing pLX304_zeo_mmFbxw7_R505C

Articles
Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of the PI3K-AKT signalling axis. Bengoechea-Alonso MT, Aldaalis A, Ericsson J. Front Oncol. 2022 Sep 13;12:990672. doi: 10.3389/fonc.2022.990672. eCollection 2022. PubMed

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